AI Networking Cookbook: Practical recipes for AI-assisted network automation and development
TL;DR
This study provides robust genetic evidence that circulating 25(OH)D levels are not a major causal determinant of HNC risk and that the instruments are not confounded by major lifestyle or UV-related factors.
ABSTRACT We examined the association between serum uric acid (UA) levels and cancer incidence through a conventional observational and two‐sample Mendelian randomization (MR) study in the same population (triangulation). We followed 13,695 individuals aged 35–69 years for cancer incidence (total, gastric, colorectal, l...
Background A growing body of evidence implicates vitamin D deficiency (VDD) in carcinogenesis, yet evidence linking VDD to female genital cancers remains inconsistent, with most studies evaluating individual cancer subtypes in isolation using heterogeneous designs. Methods We conducted a retrospective propensity score-...
Serum 25(OH)D and dietary intake showed no significant pooled associations, whereas VDR FokI was associated with increased gastric cancer susceptibility, whereas the absence of paediatric evidence highlights an important knowledge gap.
Genetic evidence of potential associations between antidepressant use and increased risks of Hashimoto's thyroiditis and hypothyroidism is provided, and support consideration of thyroidfunction monitoring in patients receiving antidepressant treatment, particularly those with pre-existing thyroid risk factors.
An independent observational association between hyperthyroidism and an increased risk of HDP is demonstrated, and supportive genetic evidence for a possible bidirectional association between genetically predicted TSH and HDP is provided.
Purpose Emerging evidence suggests a potential association between oral cavity cancer (OCC) and lymphoma. This study aimed to investigate whether this association reflects a causal relationship. Materials and Methods A two-sample bidirectional Mendelian randomization (MR) approach was utilized to screen genetic instrum...
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