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Review

BioPROTACs: a promising approach for targeted protein degradation.

Yu-Yang Li Fu-Ru Zhang Ren-Shuai Zhang Dong-Ling Shao Li-Li Yang Xin-Yu Wang Xue-Wei Cao Shu-Ang Sun Rui-Xin Ge Song-Bo Xie
Sep 2026 · Acta Pharmacologica Sinica · 0 citations · 33 references
Medicine

TL;DR

The molecular mechanisms, recent advances, and emerging applications of bioPROTAC technology are summarized, the current technical challenges are evaluated, potential strategies to address these limitations are discussed, and future directions that may facilitate its clinical translation are highlighted.

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