TL;DR
The developed crosslinker-free SA/CNC/PVA composite sponges function as cytocompatible macromolecular carriers in which cellulose nanocrystals act as structural nanofillers regulating matrix architecture and drug release behavior.
In this study, novel 3D bioprinted composite scaffolds were developed using Polyvinyl alcohol (PVA), chitosan (CS), sodium alginate (Alg), and turmeric (Tur) to investigate their potential as advanced bioactive platforms for wound healing and drug delivery. The scaffolds were fabricated via extrusion-based bioprinting,...
Overall, ZnONPs improved antibacterial activity, HAp provided the most favorable cytocompatibility and stability profile, while GONs showed a comparatively higher hemolytic response, highlighting the importance of nanoparticle selection in designing PVA/SA hydrogel scaffolds for tissue-contact applications.
It is demonstrated that the Alg/PGP/Ery hydrogel holds great promise as an advanced dressing for infected cutaneous wound repair.
This work presents a mechanically robust, highly efficient, and exceptionally safe light-activated platform for advanced wound dressing applications and demonstrates strict biosafety without collateral phototoxicity.
Bone defects caused by trauma, degenerative disorders and congenital abnormalities remain a major clinical challenge, necessitating the development of bioactive scaffolds that can promote effective bone regeneration. In this study, a composite scaffold composed of sodium alginate, polyvinyl alcohol and nanocellulose wa...
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