Skip to content
Log in
Sponsored AI AM CLAUDE, A Beginner's Guide: Learn the basics of working with AI AI AM CLAUDE, A Beginner's Guide: Learn the basics of working with AI
Review

Advances in applications of siRNA in cancer therapy: challenges and opportunities.

Mohamad Mehrparvar Shima Shabani Farshid Oruji Saba Hajazimian Hadi Nasiri S. Khansalar Javad Behroozi A Isazadeh Morteza Akbari
Jul 2026 · Clinical and Translational Oncology · 0 citations · 81 references
Medicine

TL;DR

The potential of siRNA as a promising therapeutic tool in oncology is highlighted while emphasizing the need for further research to optimize its clinical translation.

DOI PubMed Semantic Scholar
View source

Similar papers

Review Sep 2026

siRNA and mRNA Therapeutics: A Comprehensive Review of Mechanisms, Delivery Strategies, Clinical Applications, and Future Directions in Precision Pharmacology.

Small interfering RNA (siRNA) and messenger RNA (mRNA) therapeutics represent transformative approaches in precision pharmacology, enabling targeted gene silencing and protein expression, respectively. This review provides a comprehensive analysis of their molecular mechanisms, delivery strategies, clinical application...

Ritu Dahiya, A. Singh, Pooja Mathur et al. · 0 citations
Review 2026

Emerging trends in nanomedicine: The role of RNAi-based therapies and onpattro’s clinical journey

Onpattro, the first FDA-approved RNAi therapy, is highlighted, Onpattro’s clinical development is highlighted, compares delivery platforms, discusses translational challenges, and emerging technologies that will guide the next generation of RNAi nanomedicines in personalized therapy are examined.

Dilpreet Singh, Satvir Singh, Nitin Tandon et al. · 1 citation
Review Open access Aug 2026

THERAPEUTIC ROLE OF siRNA IN GASTRIC CANCER: GENE SILENCING MECHANISMS AND NANOCARRIER-BASED DELIVERY STRATEGIES.

Overall, siRNA-based strategies may play a crucial role in the future development of precision-oriented therapeutic frameworks in GC research, and this review emphasizes the integration of molecular target selection with delivery system design in a GC-specific context.

Gheysar Seifollahnezhad, B. Erdağ · 0 citations
Review Aug 2026

Exploring the Potential of CRISPR-Cas9 in Carcinoma Therapy: Advances, Challenges and Future Perspectives.

The mechanisms of CRISPR-Cas9 gene editing, recent technological advancements, and prospects for cancer management are explored and insights into strategies for precise delivery, improved targeting accuracy, and the regulatory considerations surrounding CRISPR-Cas9 for oncological applications are provided.

Nikhil Rawal, Shruti Batra, Tanu Sharma et al. · 0 citations
Review Open access Sep 2026

Advanced Nanocarriers for Cancer Therapies: Recent Developments and Clinical Challenges

This review critically summarizes recent developments in advanced nanocarriers for cancer therapy, emphasizing their design principles, therapeutic applications, clinical translation, and the key challenges influencing their future clinical adoption.

Aliya Rehmani, Palak Ghanshyam Rahangdale, Payal Dilip Meshram · 0 citations
Review Aug 2026

Protein Nanomedicine in Breast Cancer Therapy: Targeting Strategies, Clinical Applications, and Future Perspectives

The present review examines the possibilities of using protein-based nanomedicine in breast cancer treatment by looking at targeted drug delivery, immune modulation, and the mechanism of enhanced permeability and retention (EPR) for the precise targeting of the tumour.

S. H. Almurisi, Chua-Hsuan Kai, Foo Yoong Kit et al. · 0 citations

We use cookies to run the site and, with your consent, for analytics and to show ads. See our Cookie Policy.