ProToMEx: Rapid, Interpretable Explanations via Structured Representations
Athina GeorgaraAdarsh ValoorSarvapali D. Ramchurn
Sep 2026
Machine Learning
Abstract
Existing post-hoc explainers for machine learning classifiers primarily focus on feature attribution, assigning importance scores to individual features. While valuable, this approach struggles to articulate the complex, combinatorial patterns that often drive a model's decision-making process. To overcome this limitation, we introduce ProToMEx, a new paradigm for explainability that leverages Probabilistic Topic Models (PTMs). Our model-agnostic framework learns latent ''topics'' that represent distinct, high-level reasons for a classification, moving beyond simple feature importance to reveal underlying semantic structures. ProToMEx naturally provides both global explanations of a model's overall behaviour and local explanations that can disentangle multiple co-existing reasons for a specific prediction. We demonstrate empirically that ProToMEx not only produces explanations of comparable fidelity to popular methods like SHAP and LIME but also drastically reduces the amortised computational cost of generating local explanations, making it highly suitable for real-time applications. Specifically, we show that ProToMEx is ~30-40x faster than SHAP and LIME over standardised tabular datasets and synthetic datasets.
The results indicate that software engineering work practices are chosen opportunistically, adapted and configured to provide value under the constrains imposed by the startup context.
Nicolò Paternoster, Carmine Giardino, M. Unterkalmsteiner et al.· Information and Software Tec...· 394 citations· ⚡54
The possibility of inferring high-dimensional data inference in a model that consists of a prior and an auxiliary differentiable constraint given some additional information is considered, thereby allowing a range of potential applications in adapting models to new domains and tasks.
Alexandros Graikos, Esmeralda S. Whitammer, N. Jojic et al.· Neural Information Processin...· 316 citations· ⚡15
It is proved that any global minimizer of the trajectory balance objective can define a policy that samples exactly from the target distribution, and empirically demonstrate the benefits of the trajectories balance objective for GFlowNet convergence, diversity of generated samples, and robustness to long action sequences and large action spaces.
Esmeralda S. Whitammer, Moksh Jain, Emmanuel Bengio et al.· Neural Information Processin...· 302 citations· ⚡60
This state-of-practice investigation was performed using a literature review followed by a multiple-case study approach and presents how inconsistency between managerial strategies and execution can lead to failure by means of a behavioral framework.
Carmine Giardino, Xiaofeng Wang, P. Abrahamsson· International Conference on...· 175 citations· ⚡19
This study conducts a case survey study based on the secondary data of the major pivots happened in 49 software startups, and demonstrates that customer need pivot is the most common among all pivot types.
Sohaib Shahid Bajwa, Xiaofeng Wang, Anh Nguyen-Duc et al.· Empirical Software Engineeri...· 127 citations· ⚡15
Minimum viable product (MVP) is the main focus of both business and product development activities in software startups. We empirically explored five early stage software startups to understand how MVP are used in early stages. Data was collected from interviews, observation and documents. We looked at the MVP usage from two angles, software prototyping and boundary spanning theory. We found that roles of MVPs in startups were not fully aware by entrepreneurs. Besides supporting validated learning, MVPs are used to facilitate product design, to bridge communication gaps and to facilitate cost-effective product development activities. Entrepreneurs should consider a systematic approach to fully explore the value of MVP, as a multiple facet product (MFP). The work also implies several research directions about prototyping practices and patterns in software startups.
Anh Nguyen-Duc, P. Abrahamsson· International Conference on...· 92 citations· ⚡9
A new machine-learning framework aims to improve the success rate of computational protein design while moving away from results that reproduce sequences found in nature.
MIT News · Artificial Intelligence· news.mit.eduAug 24, 2026