AI Networking Cookbook: Practical recipes for AI-assisted network automation and development
TL;DR
This review critically evaluates recent advances in indole-based anticancer agents, with particular emphasis on structure–activity relationships (SAR), molecular mechanisms, and target-oriented drug design.
Pyrimidine-containing hybrids emerge as a privileged scaffold in medicinal chemistry for the development of effective, multitargeted anticancer agents with improved pharmacological profiles and reduced off-target effects.
A target‐oriented overview of quinoline‐based anticancer agents reported between 2019 and 2025, covering quinoline, quinazoline, quinoxaline, and a few selected nonquinoline nitrogen‐containing heterocyclic derivatives is provided.
Overall, quinoxaline represents a flexible platform for developing multifunctional and target-directed anticancer agents with potential applications across diverse cancer-associated pathways.
This review outlines synthetic strategies for N-((5-phenyl-1H-pyrazol-3-yl) carbamothioyl) benzamide derivatives, evaluates their biological activity, and discusses structure–activity relationships (SAR).
This review is an attempt to bridge the gap between synthetic structural biology and translational oncology by systematically connecting the structure- activity relationships of novel triazole hybrids targeting Aromatase, VEGFR-2, IDO1, and Carbonic Anhydrase.
Bioactive heterocyclic nuclei remain flexible and clinically proven platforms for the creation of novel anticancer treatments and the integration of bioactive scaffold optimization with precision oncology, computational technologies, biomarker-guided design, and novel target-modulation techniques will be necessary for...
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