Aug 2026· Frontiers in Digital Health· Vol 8· 0 citations· 45 references
Medicine
TL;DR
An exploratory weakly supervised NLP analysis of positive/negative affective-tone proxies in AphasiaBank transcripts with paired audio highlights both the promise of clinical NLP for aphasia discourse analysis and the need for independent human-labeled validation, utterance-aligned acoustic features, and careful control of domain, task, age, and topic bias.
Abstract
Introduction Aphasia affects expressive and receptive communication and may influence the affective tone expressed during clinical speech tasks. This study presents an exploratory weakly supervised NLP analysis of positive/negative affective-tone proxies in AphasiaBank transcripts with paired audio. Methods We extracted sentence embeddings from DistilBERT (e∈R768) and recording-level acoustic summaries (MFCC13, ZCR, RMS, spectral centroid, and spectral bandwidth; a∈R17). Text and acoustic features were concatenated (x=[e;a]∈R785) and classified using Random Forest models. Sentiment labels were generated using an SST-2-derived weak-supervision pipeline and should be interpreted as pseudo-labels rather than clinical ground truth. To evaluate modality contribution and potential leakage, we compared text-only, audio-only, and fused text-audio models under utterance-level and recording-disjoint splits. A small five-rater evaluation was used to examine human judgment alignment. Results Under the recording-disjoint split, both the text-only and fused text-audio models achieved 97.9% accuracy and 0.791 macro-F1, while the audio-only model achieved 55.4% accuracy and 0.388 macro-F1. These results indicate that classification performance was primarily driven by textual embeddings, while the recording-level acoustic summaries did not improve performance over text-only features. Across the pseudo-labeled corpus, aphasic utterances were more often labeled negative than control utterances. Age-stratified summaries showed subgroup variation in pseudo-label distributions, but these patterns were treated descriptively because labels were model-derived. Human-rater agreement was low for aphasic utterances, indicating that affective-tone interpretation in fragmented clinical speech is ambiguous. Discussion These findings should be interpreted as exploratory evidence about weakly supervised affective-tone proxies, not as validated clinical sentiment recognition. The results highlight both the promise of clinical NLP for aphasia discourse analysis and the need for independent human-labeled validation, utterance-aligned acoustic features, and careful control of domain, task, age, and topic bias.
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