Aug 2026· Naunyn-Schmiedeberg's Archives of Pharmacology· 0 citations· 100 references
Medicine
TL;DR
A review of the available information regarding the natural sources, methods of extraction, chemical structure, and biological and therapeutic actions of GPA identifies knowledge gaps and outlines further research directions necessary for the development of GPA as a potential therapeutic agent.
Despite promising pre-clinical findings, clinical evidence supporting its therapeutic efficacy remains limited and future research should prioritize well-designed human clinical studies and improved standardization strategies to facilitate the translation of O. stamineus into evidence-based therapeutic applications.
M. Naveen, S. Padmapriya, T. Saraswathi et al.· 0 citations
Baiyaozi is the dried tuber of Stephania cepharantha, a plant belonging to the genus Stephania in the family Menispermaceae, and is a traditional Chinese medicine. This study conducted a systematic review of relevant literature from databases such as PubMed and Web of Science to discuss the structural characteristics a...
Jin-Shuo Ma, Nai-Bei Hou, Ying-Ying Wang et al.· Natural Product Communicatio...· 0 citations
Although C. citrinus has remarkable therapeutic promise, the paucity of clinical studies and pharmacokinetic data, and the lack of standardization hinder its clinical translation, and there is a need for clinical trials to prove its potential therapeutic benefits.
Shankul Kumar, Vedant Kumar Prajapati, A. Patel et al.· Current Chemical Biology· 0 citations
The findings underscore the promising pharmacological potential of L. cernuum and highlight the need for rigorously designed studies, particularly well-controlled clinical trials and mechanistic investigations, to validate its efficacy and safety and to inform its rational development as a therapeutic agent.
Rollando Rollando, Dodi Iskandar, V. Kharisma et al.· Majalah Obat Tradisional· 0 citations
Overall, Coccinia grandis is a rich natural resource with important pharmacological applications and an increasing promise for future drug development and nanomedicine.
N. Sengar, Avijit Mazumder, Saumya Das· Drug Delivery Letters· 0 citations
C. nutans demonstrates significant medicinal potential, and future research priorities should include bioactivity-guided isolation of novel metabolites, validated in vivo mechanistic studies, pharmacokinetic and metabolomic profiling, and the implementation of standardized Phase I/II clinical trials and veterinary eval...
Wen-Xuan Si, Xin-Yue Sun, Yuan-Bin Han et al.· Frontiers in Pharmacology· 0 citations
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