Open access

Early‐life internalizing behavioral trajectories and childhood‐onset asthma: An epigenetic link

Jisun Yoon Seung-Hwa Lee Jiseon Kim Kyungmo Hong So-Yeon Lee H. Oh Sung-Su Jung Da-Kyeong Lee Eom Ji Choi Ji Soo Park Y. Shin Kyung Won Kim Kangmo Ahn Jihyun Kim Y. Shin Kyung-Sook Lee D. Suh Soo-Jong Hong

Aug 2026 · Pediatric Allergy and Immunology · Vol 37 · 0 citations · 32 references

Medicine

TL;DR

Whether early‐life behavioral problem trajectories affect the risk of childhood asthma and potential DNA‐methylation mechanisms are investigated and potential DNA‐methylation mechanisms are ascertained.

Abstract

Behavioral problems and asthma in childhood are considered related despite the debatable causal relationship and unknown mechanisms. We investigated whether early‐life behavioral problem trajectories affect the risk of childhood asthma and ascertained potential DNA‐methylation mechanisms.

DOI PubMed Semantic Scholar

Read PDF

Similar papers

Open access Aug 2026

Eating Behavior Latent Profiles and Their Associations With Body Composition in Early Childhood: The CORALS Cohort

This study aimed to identify sex‐specific eating behavior profiles and assess the associations between eating behaviors subscales and profiles and body composition indices in Spanish preschoolers from the CORALS cohort.

Andrea Jimeno-Martínez, M. Miguel-Berges, I. Maneschy et al. · Obesity · 0 citations

Open access Sep 2026

Postnatal growth and childhood asthma in preterm and full‐term twins: A cohort study

The role of postnatal growth in asthma development in children remains unclear. We examined the association between postnatal growth pattern and childhood asthma and assessed whether this association differed between preterm and full‐term children.

R. R. Putri, C. Lundholm, M. Mubanga et al. · Pediatric Allergy and Immuno... · 0 citations

Review Open access Sep 2026

Childhood cancer and future cardiometabolic health

Childhood cancer survivors face an elevated risk of cardiometabolic disease that can emerge years after treatment completion. This Review summarises the mechanisms underlying this vulnerability, the contribution of biological, social, and lifestyle factors across the life course, and emerging opportunities for early pr...

Abel Plaza-Florido, Pedro Carrera-Bastos, Shlomit Radom-Aizik et al. · npj Metabolic Health and Dis... · 0 citations

Open access Sep 2026

Placental Growth Factor Trajectories During Pregnancy and Child ADHD.

This cohort study examines whether placental growth factor trajectories during pregnancy differ across trimesters in women whose children later received an attention-deficit/hyperactivity disorder (ADHD) diagnosis.

S. Gumusoglu, A. Betz, Andy Storm et al. · JAMA psychiatry · 1 citation

Open access Sep 2026

Trajectories of late‐life job insecurity and labor force participation: Associations with cognitive function and impairment in the Health and Retirement Study's harmonized cognitive assessment protocol

Continued workforce participation may preserve later‐life cognition, yet many Americans face job insecurity and instability in later life, with potential consequences for cognitive aging.

Erika T. Beidelman, Xue-Xin Yu, Constance Beaufils et al. · Alzheimer's & Dementia · 0 citations

Open access Sep 2026

Perceived Family Functioning, Family Resilience, and Multidimensional Sleep Problems Among Chinese Children and Adolescents With Cancer: The Indirect Association of Depression and Anxiety

A large number of children and adolescents with cancer have sleep problems and the contributions of depression and anxiety remain unquantified, and perceived family functioning and family resilience are known to be associated with sleep problems.

Zhe Li, Chao-Ran Hu, Li-Jia Yao et al. · Cancer Medicine · 0 citations