Analysis of current status of knowledge, attitudes, and influencing factors regarding chikungunya fever among medical staff in Chengdu, Sichuan province, China: a cross-sectional study
Jul 2026· Frontiers in Public Health· Vol 14· 0 citations· 21 references
Medicine
TL;DR
Chengdu medical personnel demonstrated general CHIK knowledge and positive attitudes, yet significant operational gaps persist in early detection and reporting protocols, highlighting the need for standardized, process-oriented training emphasizing diagnostic and reporting procedures.
Abstract
Background Chikungunya (CHIK) is an emerging mosquito-borne disease with increasing importation risk in China. In non-endemic settings, delayed detection may facilitate local transmission, making healthcare workers’ knowledge and attitudes critical for rapid response. Objective To assess CHIK-related knowledge and attitudes among medical personnel in Chengdu, Sichuan Province, and identify factors associated with positive prevention attitudes. Methods A cross-sectional, self-administered online survey was executed from July 30 to August 6, 2025, targeting medical workers across 20 healthcare institutions in Chengdu using the Wenjuanxing platform. The questionnaire gathered demographic information, CHIK-related training exposure (yes/no), and assessments of knowledge and attitudes. Knowledge was assessed using 15 items (range 0–15; 1 point awarded for each right response). Attitudes were evaluated using Likert-type items; a cumulative attitude score of ≥20 signified a favorable attitude. Group disparities were analyzed with Chi-square tests alongside suitable parametric and nonparametric assessments. Hierarchical logistic regression (Block 1: demographics/occupational characteristics; Block 2: training; Block 3: knowledge score) was employed to ascertain factors correlated with positive attitudes. Results 1,092 questionnaires were included, yielding an effective response rate of 90.10%; 83.70% indicated they had received training relevant. The average knowledge score was 11.66 ± 2.15. Despite high performance in primary prevention and clinical management, significant deficiencies were noted in early detection and surveillance-related operational knowledge: merely 42.58% accurately interpreted the RT-PCR Ct criterion, 54.85% recognized suspected cases, 56.14% comprehended diagnostic criteria, and 59.80% were aware of the 24 h online reporting requirement. Knowledge scores were elevated among individuals with advanced education, physicians, tertiary hospital personnel, and those who had training (p < 0.05). Attitude scores varied according to age, job type, hospital type, practice category, years of experience, and professional title (p < 0.05). In hierarchical logistic regression, training (OR = 3.971, p < 0.001) and elevated knowledge scores (OR per point = 1.130, p < 0.001) were independently linked to a favorable prevention-and-control attitude. Conclusion Chengdu medical personnel demonstrated general CHIK knowledge and positive attitudes, yet significant operational gaps persist in early detection and reporting protocols. Training and knowledge are key determinants of favorable attitudes, highlighting the need for standardized, process-oriented training emphasizing diagnostic and reporting procedures.
Background: Antibiotic resistance (AMR) is a critical global health threat, often exacerbated by inappropriate self-medication. In Indonesia, infectious diseases remain a leading cause of mortality, yet public understanding of and practices regarding antibiotic use are often suboptimal. Objective: This study investigated the association between sociodemographic factors and knowledge, beliefs, attitudes, and practices (KAP) regarding antibiotic use in the community in Bandar Lampung, Indonesia. Methods: A community-based cross-sectional survey was conducted from March to April 2023 across 31 primary healthcare centers in 17 sub-districts. A total of 418 respondents were selected using a two-stage cluster sampling method. Data were collected using a validated questionnaire (Cronbach’s alpha > 0.6) and analyzed using Chi-square and Fisher’s exact tests (p<0.05). Results: The findings showed that 53.35% of respondents had inadequate knowledge, and 49.76% practiced self-medication. Although 94.50% held favorable attitudes toward rational use, a notable "attitude-practice gap" persisted. Statistical analysis found that sociodemographic factors, including age, education level, and health insurance, were not significantly associated with knowledge, beliefs, or attitudes (p>0.05), indicating that misconceptions were uniformly distributed across the community. However, antibiotic-use practices were significantly associated with gender (p=0.038) and occupation (p=0.027). Furthermore, knowledge levels were significantly associated with self-medication practices (p=0.028), identifying inadequate health literacy as a primary driver of inappropriate drug acquisition. Conclusion: Although theoretical attitudes were positive, inadequate knowledge and easy access to medication fueled high rates of self-medication. Pharmacists must serve as clinical gatekeepers and implement community-wide educational interventions to correct misconceptions and promote rational antibiotic therapy
Annisa Primadiamanti, Gusti Ayu Rai Saputri, Nurma Suri et al.· INPHARNMED Journal (Indonesi...· 0 citations
Malaria remains a public health concern in Indonesia, particularly in Indonesia's New Capital City (IKN) development area, where environmental changes and worker mobility may increase transmission risk. This study aimed to examine the association between knowledge, attitude, risk perception, and malaria control among workers in the IKN area. A cross-sectional study was conducted among 167 workers in the IKN development area, East Kalimantan, Indonesia. Data were collected using validated self-administered questionnaires. Chi-square tests were used to examine bivariate associations, and multiple binary logistic regression was performed to identify the strongest factor associated with malaria control behavior. Most respondents had moderate knowledge (46.7%), positive attitudes (57.5%), good risk perception (55.1%), and good malaria control behavior (54.5%). Knowledge (p=0.001), attitude (p=0.001), and risk perception (p=0.001) were significantly associated with malaria control. Multivariate analysis showed that risk perception was the strongest determinant (OR=8.559; 95% CI=3.184-23.004), followed by knowledge (OR=6.309; 95% CI=2.145-18.552) and attitude (OR=4.558; 95% CI=1.732-11.994). Knowledge, attitude, and risk perception were significantly associated with malaria control among IKN workers, with risk perception emerging as the dominant factor. These findings contribute evidence for strengthening workplace-based malaria prevention through contextual health education, routine risk communication, early screening, and environmental control in rapidly developing occupational settings.
Raden Mohammad Pradendi Nikita Sangaji, Yunianto Setiawan, Ike Anggraeni Gunawan· Jurnal Kesehatan Budi Luhur...· 0 citations
Background HIV post-exposure prophylaxis (PEP) is effective when initiated promptly and used correctly, but uptake remains limited partly because potential users and future providers may not recognize when or how PEP should be used. Medical students are relevant for assessment because they represent future clinicians and may also encounter occupational exposure during training. Evidence on PEP-specific knowledge and attitudes among Chinese medical students remains limited. Methods We conducted a multi-center cross-sectional survey between March and August 2025 among 1,382 medical students at three medical schools in China. A structured 54-item online questionnaire assessed PEP knowledge, PEP attitudes, and HIV-related stigma. Knowledge and attitude scores were analyzed as continuous outcomes. Multivariable linear regression models were used to examine factors associated with knowledge and attitudes. Results The mean PEP knowledge score was 12.1 (SD = 4.3) on a 0–20 scale, and the mean attitude score was 52.8 (SD = 8.6) on a 15–75 scale. Knowledge was highest for basic PEP definition, the 72-h initiation window, and the 28-day regimen, but lower for delaying PEP until a baseline HIV test result is available, the HIV testing window period, and cost-related access. In adjusted analyses, higher knowledge was associated with academic year (beta = 0.26), prior PEP training (beta = 0.22), formal HIV curriculum exposure (beta = 0.12), and attendance at Site 1 relative to Site 3 (all p < = 0.004). More favorable attitudes were associated with higher knowledge (beta = 0.28), prior PEP training (beta = 0.15), clinical rotation completion (beta = 0.09), female sex (beta = 0.07), and attendance at Site 1 relative to Site 3 (all p < = 0.022). Knowledge and attitude scores were positively correlated (r = 0.29, p < 0.001). Conclusion In this large multi-site convenience sample, PEP knowledge was uneven and was weaker for applied clinical details than for general facts, whereas attitudes toward PEP were broadly favorable. Prior PEP-specific training was consistently associated with stronger scores. Because recruitment relied on institutional WeChat distribution rather than probability sampling, the findings should be interpreted as evidence from participating schools and should not be generalized directly to all medical students in China.
Maoqi Xiong, Xiao He, M. He et al.· Frontiers in Public Health· 0 citations
Background Tuberculosis (TB) remains the leading infectious cause of death from a single pathogen, disproportionately affecting low- and middle-income countries. Sudan’s TB burden has been compounded by prolonged armed conflict and deteriorating health infrastructure, yet no published study has assessed TB-related knowledge, attitudes, and self-reported practices (KAP) among Sudanese medical students. This study assessed TB-related KAP among medical students at the University of Khartoum and explored sociodemographic predictors of KAP outcomes. Methods A cross-sectional survey was conducted at the Faculty of Medicine, University of Khartoum, Sudan (August–October 2024), using a proportionally allocated stratified convenience sample of 311 undergraduate medical students from the third to sixth academic years (response rate 91.5%). A validated, self-administered questionnaire assessed sociodemographic characteristics, TB knowledge (10 items), attitudes (7-item Likert scale), and self-reported preventive practices (5 items). Associations between KAP domains were examined using Pearson correlation, and multiple linear regression identified sociodemographic predictors of each domain, adjusting for sex, age group, and academic year (SPSS version 29). Results The mean knowledge score was 6.43 ± 2.52 out of 10 (64.3%), indicating moderate overall knowledge. Correct responses were common for TB etiology (94.9%) and airborne transmission (91.3%) but less common for latent TB non-infectiousness (29.3%) and tuberculin skin test (TST) interpretation (49.2%). The mean attitude score was 27.90 ± 4.27 out of 35, and the mean self-reported practice score was 19.55 ± 3.67 out of 25; only 28.3% reported consistently wearing a face mask when interacting with suspected or confirmed TB patients. Knowledge correlated weakly with attitude scores (r = 0.179, p = 0.001) and was not significantly correlated with practice scores (r = 0.090, p = 0.113); attitude and practice scores were moderately correlated (r = 0.437, p < 0.001). Among the sociodemographic variables assessed, academic year was the strongest predictor of knowledge scores (adjusted R² = 0.474, p < 0.001), whereas the attitude and practice models explained minimal variance (adjusted R² = 0.029 and 0.018, respectively); female sex was the only significant predictor of self-reported practice (B = 0.95, 95% CI: 0.09–1.80, p = 0.031). Conclusions In this single-institution study, medical students at the University of Khartoum demonstrated moderate knowledge of core tuberculosis concepts, with particular strength in disease causation and transmission but important gaps in latent tuberculosis infection and tuberculin skin test interpretation. Knowledge was weakly associated with attitudes and was not associated with self-reported preventive practices, suggesting that factual knowledge alone may not be sufficient to promote corresponding behavior. Given the convenience-sampling design and single-institution setting, these findings should be interpreted as an educational snapshot rather than generalized to all Sudanese medical students; they may nonetheless inform curriculum discussions on reinforcing tuberculosis-related knowledge, attitudes, and preventive practices.
In Yemen, dengue is one of the major public health concerns. Cases have been recorded in almost all governorates in Yemen. In 2019, the Hodeidah governorate had the second highest death rate in the country. Adequate public knowledge, attitudes, and practices (KAP) regarding dengue prevention are essential for effective disease control. This study aims to assess KAP about dengue fever among the communities in Hodeidah, Yemen. A community-based cross-sectional study was conducted from June 1 to December 30, 2019, among population residing in six districts of Hodeidah governorate, Yemen. A total of 422 participants were selected using a stratified multistage cluster sampling technique and interviewed face-to-face using a pretested structured questionnaire. Data were analyzed using SPSS version 25. Mann-Whitney, Kruskal-Wallis, and Spearman's correlation analysis were used for analysis. Logistic regression analysis was conducted to identify independent predictors of good dengue practices. Crude and adjusted odds ratios (AOR) with 95% confidence intervals (CI) were calculated, and p-values < 0.05 were considered statistically significant. The results revealed that only 2.8% of participants demonstrated good knowledge regarding dengue fever, while 32.9% showed positive attitudes and 11.6% reported good preventive practices. Weak but significant positive correlations were found between knowledge and attitude (r = 0.103, p = 0.035) and between knowledge and practice (r = 0.313, p < 0.001). Knowledge scores were significantly associated with residence, occupation, and educational level (p < 0.001). Attitude scores differed significantly by residence and age group, whereas practice scores differed by residence and sex. Female participants were more likely to demonstrate good dengue prevention practices than males (AOR = 2.41, 95% CI: 1.56-3.67, p < 0.001). Overall knowledge and preventive practices regarding dengue fever were poor among residents of the Hodeidah governorate. Strengthening community-based health education and public participation in dengue prevention and vector control programs is recommended.
Mohammed Ahamed Hajjam, Ahlam Bin Briek· Scientific Reports· 0 citations
Introduction: Antimicrobial resistance (AMR) is one of today's biggest public health challenges. Fighting this global public health threat requires cross-sector cooperation. Thus, this study examined the knowledge, attitudes, and practices (KAP) of inhabitants and health care workers (HCWs) in Al-Suwaria City at Wasit province, Iraq about AMR. Methods: This study used 125 random contributors for cross-sectional analysis from January to April 2024. A questionnaire gathered participants' demographic information, as well as their antibiotic resistance knowledge, attitudes, and behaviors. The data was analyzed using a Statistical Analysis System (SAS). Results: According to knowledge evaluation questions, only 43.75% demonstrated a good understanding of AMR. There are also knowledge gaps in the ability to use antibiotics to treat viral infections (24.0%) and tackle antibiotic resistance by discovering novel medicines (56.0%). Additionally, high rates of participants (50.4%) strongly agreed on the need to governor over-the-counter (OTC) antibiotic administration, while 47.2% had weak attitudes toward healthcare professionals' infection control practices combating AMR in their region. Regarding practices to AMR, our findings showed that 57.14% of responders had insufficient procedures. While the knowledge and attitude of the participants in this study were significantly correlated (p ≤ 0.01), the knowledge and practices (p = 0.266) and attitudes and practices (p = 0.6072) did not show a significant correlation (p ≥ 0.05). Conclusions: An educational intervention tailored to individuals and HCWs' sociodemographic and professional characteristics is needed to bridge theory and practice and enhance attitudes and practices.
M. Kanaan, I. H. Dhefer, Ahmad M. Tarek et al.· International Journal of Nut...· 0 citations
