Aug 2026· Stem Cell Research· Vol 95, pp.
104093
· 0 citations· 3 references
Medicine
Abstract
Induced pluripotent stem cell (iPSCs) line, NIMHi034-A has been generated from peripheral blood mononuclear cells (PBMCs) of a 59-year-old healthy Indian adult male using non-integrating Sendai viral reprogramming vectors in a feeder free method. The iPSCs exhibit normal karyotype, express markers of undifferentiated state and could differentiate in-vitro into cells of three germ layers. This cell line can serve as a healthy control for various disease models and in deciphering disease mechanisms.
Patients with synchronous multiple primary malignancies often exhibit unique genetic susceptibility. Here, we generated the induced pluripotent stem cell (iPSC) line, SHUTCMi001-A, from a 70-year-old patient with double primary lung squamous cell carcinoma and sigmoid colon adenocarcinoma with wild-type driver genes. T...
Jing-Yi Wei, Guan-Jin Wu, Chen-Bing Sun et al.· Stem Cell Research· 0 citations
Mesenchymal stromal cells (MSCs) are key components of the bone marrow (BM), providing structural support and paracrine signals that regulate haematopoietic stem cell maintenance, self-renewal and differentiation. However, primary BM MSCs are rare, heterogeneous, and subject to donor variability and have limited ex-viv...
Liani G. Devito, Khadidja Habel, Ruta Meleckyte-Martinez et al.· Stem Cell Research· 0 citations
This patient-specific iPSC line provides a valuable resource for generating choroid plexus organoids and neurons to investigate disease mechanisms and develop therapeutic strategies to investigate disease mechanisms and develop therapeutic strategies.
Weronika Przybala, Swapnil Gupta, H. Fjerdingstad et al.· bioRxiv· 0 citations
Nephronophthisis, an autosomal recessive ciliopathy, is a rare genetic kidney disorder characterized by progressive tubulointerstitial fibrosis, corticomedullary cyst formation, and progression to end-stage renal disease. Here, we established a human induced pluripotent stem cell (hiPSC) line from peripheral blood mono...
Jeeyoung Yoon, Y. Shin, Han-Bi Lee et al.· Stem Cell Research· 0 citations
High-quality, standardized iPSC reference lines are crucial for disease modeling and regenerative medicine. We generated and extensively characterized thirteen iPSC clones from PBMCs of five healthy donors (three female, two male) using non-integrating Sendai virus. This resource is distinguished by its standardized de...
E. Stein, Ellen Mosca, Jiss John et al.· Stem Cell Research· 0 citations
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