Skip to content
Preprint

Partial Identification Learning with Categorical Treatments for Individualized Treatment Rules

Aug 2026 · 0 citations · 38 references
Mathematics

Abstract

We develop a partial identification learning framework for individualized treatment rules (ITRs) with categorical treatments, outcomes, and instrumental variables. Rather than relying on strong causal assumptions required for point identification, our framework leverages causal bounds to characterize the optimal treatment decision. Existing methods for ITR optimization under partial identification are largely restricted to binary treatment settings and the bounds derived by Balke and Pearl under the canonical instrumental variable design. We extend this framework to accommodate a broader class of causal structures as well as scenarios with categorical treatment, outcome, and instrumental variables. We introduce a generalized minimax loss criterion for treatment selection from among more than two options, which minimizes the maximum possible difference between the chosen and the optimal treatment based on partial identification bounds. To construct the ITR, we use a symmetric embedding strategy that maps discrete treatments to the vertices of a regular simplex, avoiding the geometric inconsistencies of standard one-vs-rest approaches. We derive a differentiable, weighted surrogate risk function and show that optimizing it solves the original problem. Furthermore, we provide finite sample convergence rates via an oracle inequality under general regularity conditions, which we show are satisfied by a kernel based implementation. Numerical experiments demonstrate that the framework yields ITRs significantly closer to the oracle ITR compared to existing alternatives in settings with unmeasured confounding.

View source

Similar papers

Preprint Aug 2026

Orthogonal double residual learning for optimal individualized treatment rules

Individualized treatment rules (ITRs) map baseline characteristics to treatment recommendations, with the optimal ITR maximizing expected reward or policy welfare. Indirect methods may require restrictive modeling assumptions, whereas direct methods can be sensitive to nuisance estimation error and limited overlap. We...

Jia-Qi Tong, Fan Li · 0 citations
Preprint Sep 2026

Policy evaluation and learning with partially identified utility under truncation by death

Policy evaluation and learning aim to assess and optimize treatment assignment rules based on individual characteristics. A fundamental challenge arises when outcomes are truncated by death, rendering conventional policy utilities undefined. To address this challenge, we study policy evaluation and learning under trunc...

Zi-Wei Huang, Zhi-Chao Jiang · 0 citations
Review Sep 2026

Orthogonal Policy Learning with Ordinal Outcomes

Policy learning methods based on conditional average treatment effects can obscure subpopulation heterogeneity when applied to ordinal outcomes. We develop a policy learning framework for ordinal outcomes with heterogeneous utilities for individuals who strictly benefit from treatment and those who do not. Since the pr...

Yue Zhang, Shan-Shan Luo, Yan-peng He · 0 citations
Preprint Aug 2026

Causal Effects of Modified Treatment Policies under Positivity Violations: A Partial Identification Approach

Modified treatment policies (MTPs) are interventions based on each individual's natural treatment value. We study mean outcomes under MTPs for continuous treatments, including exposure mixtures. Positivity is the standard sufficient condition for identifying these mean outcomes without extrapolation: policy-generated v...

Taehyeon Koo, Elizabeth A. Stuart, K. Rudolph et al. · 0 citations
Sep 2026

DOUBLY ROBUST OPTIMAL TREATMENT REGIME VIA NEURAL NETWORKS

The optimal treatment regime (OTR) is a recent development in personalized medicine. It assigns the best treatment to an incoming patient according to his/her covariate profile. Construction of the optimal regime hinges on unbiased estimates of the treatment effects. In observational studies, it is known that tradition...

Raul T. Aragon, Yuan Ao, Ming T. Tan · 0 citations
#machine learning Preprint Oct 2026

Targeted Active Learning for Preference-Based Treatment Effects on Multivariate Outcomes

Treatment efficacy is traditionally demonstrated on the basis of a single primary outcome. However, clinical decision-making usually requires consideration of multiple outcomes, balancing expected benefits against potential risks. The relative value assigned to these outcomes varies substantially from one patient to an...

Lola Giordani, Mathieu Even, Chloé Geoffroy et al. · 0 citations

We use cookies to run the site and, with your consent, for analytics and to show ads. See our Cookie Policy.