Skip to content

Identification of STK35L1 as a potential prognostic biomarker in breast carcinoma, and its expression exhibits high correlation with EGFR activity

Sep 2026 · Functional & Integrative Genomics · Vol 26 · 0 citations · 39 references
Medicine

TL;DR

An association of STK35L1 and EGFR in BC is reported, highlighting STK35L1 as a potential prognostic biomarker and therapeutic target and suggesting that EGFR-STAT3 signaling may regulate STK35L1 and EGFR expression.

View source

Similar papers

Open access Sep 2026

MXRA5 promotes the progression and metastasis of breast cancer via activation of the epithelial-to-mesenchymal transition pathway

Elevated MXRA5 expression exhibited a positive correlation with advanced lymph node metastasis and impaired clinical prognosis, and its potential as a valuable prognostic biomarker and therapeutic target for managing metastatic disease is revealed.

Jian Wang, Jie Tang, Yaoxin Wang · 0 citations
Open access Sep 2026

Multi-omics and experimental validation reveal ISG20L2 as a potential pro-oncogenic regulator in gastric cancer

ISG20L2 is aberrantly upregulated and associated with malignant biological features and immune-related characteristics in gastric cancer, supporting its potential role as a pro-oncogenic regulator and a candidate molecular indicator requiring further clinical validation.

Song Liang, Chuan-Jun Wang, Yong-Kang Liang et al. · 0 citations
Review Open access Aug 2026

Molecular functions, clinical correlates, and therapeutic prospects of B7-H3 expression in colorectal cancer: A systematic review.

Colorectal cancer (CRC) is the second leading cause of cancer-related death. The tumor immune microenvironment plays a critical role in tumor progression and immune evasion. B7-H3 (CD276), a member of the B7 family of immune checkpoint molecules, is frequently overexpressed in a variety of malignancies, including CRC....

Nouran Alwisi, M. Hamid, Dahab Ghith et al. · 0 citations
Sep 2026

ZUP1 as a Novel Potential Oncogenic Driver and Prognostic Biomarker in Breast Cancer.

This study identifies ZUP1 as a potential oncogenic factor and a robust independent prognostic biomarker in breast cancer and suggests that ZUP1 is a novel multifaceted biomarker with significant implications for personalized treatment strategies in breast cancer.

Weimiao Li, Changyou Shan, Shu-Qun Zhang et al. · 0 citations

We use cookies to run the site and, with your consent, for analytics and to show ads. See our Cookie Policy.