Beyond regulating sleep, the orexin/hypocretin system participates in bidirectional neuro‐immune interactions that may influence neurodegenerative diseases (NDs) and chronic inflammatory conditions. This systematic review aimed to conceptually synthesize evidence on these interactions and their clinical implicati...
J. Hakizimana, Zephyrin Izukwizabigenza, M. Kampire et al.· Clinical and Experimental Ne...· 1 citation
We synthesised current evidence on enterocyte trafficking proteins and elucidated the molecular mechanisms by which their dysfunction contributes to intestinal disease.
Search was conducted in PubMed/MEDLINE, Web of Science, and Wiley Online Library for studies published between January 2000 and March 2026...
This study aimed to characterize rare, clinically relevant genetic variants in a Rwandan pediatric ASD cohort using trio‐based whole‐exome sequencing (WES) using trio‐based whole‐exome sequencing (WES).
Olivier Hakizimana, J. Hitayezu, J. P. Uyisenga et al.· Molecular Genetics & Genomic...· 0 citations
This systematic narrative review aims to synthesize the available evidence on the role of protein sorting machinery in CFTR channelopathies and its contribution to exocrine pancreatic dysfunction to improve pancreatic function and mitigate disease progression.
Aime Patrick Niyomugabo, Leopold Ntakirutimana, A. Alagbonsi· Channels· 0 citations
The outcomes of diabetic treatment in Rwanda are associated with the age of the patients, rather than the type of therapy or the assessed sociodemographic and risk factors.
A. Alagbonsi, Aime P. N. Kagina, Denyse Ingabire et al.· Diabetes, Metabolic Syndrome...· 1 citation
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