A metabolite-guided signal fidelity hypothesis is proposed in which certain specialized metabolites act as molecular stabilizers in the response of organisms to stress and buffer transient ROS bursts, limit variability in calcium signaling, and strengthen hormone-regulated feedback loops.
M. Warda, Merve Bolat, S. Tekin et al.· Plants· 0 citations
Findings indicate that Morin exerts a strong nephroprotective effect against Cd-induced renal toxicity through attenuation of oxidative stress and inflammation, possibly associated with its antioxidant and anti-inflammatory properties.
Burak Batuhan Laçin, Furkan Aykurt, S. Tekin et al.· Erciyes Üniversitesi Veterin...· 0 citations
Overall, ZIN exhibited dose-dependent hepatoprotective and neuroprotective effects in TAA-induced hepatic encephalopathy, as evidenced by attenuation of oxidative stress, inflammation, ER stress, and apoptosis.
Furkan Aykurt, S. Yıldırım, Metin Kılıçlıoğlu et al.· Journal of Molecular Histolo...· 0 citations
