BACKGROUND
Optimal antithrombotic therapy for ischemic stroke due to symptomatic large-artery atherosclerosis in patients with atrial fibrillation remains uncertain. We describe real-world prescribing patterns and outcomes across antithrombotic regimens.
METHODS
We retrospectively analyzed consecutive patients with a...
Ghada A. Mohamed, A. de Havenon, Renee' H. Martin et al.· Journal of the American Hear...· 0 citations
INTRODUCTION
Clinical trials have found semaglutide reduces the risk of major adverse cardiovascular events (MACE) among people with type 2 diabetes (T2D) at high risk of MACE. Less is known about oral semaglutide's impact on real-world cardiovascular risk.
METHODS
This observational cohort study used administrative...
Xi Tan, Yuan-Jie Liang, Cai-Chen Zhong et al.· Diabetes Therapy· 0 citations
BACKGROUND
White matter hyperintensities (WMH) are a common brain magnetic resonance imaging marker of cerebral small vessel disease and a major risk factor for stroke and dementia, yet the molecular mechanisms governing lesion formation remain incompletely understood. We sought to identify circulating proteins that li...
C. Rivier, Sebastián Díaz-Pérez, Gael Bories et al.· Stroke· 0 citations
ABSTRACT Objective: To determine whether a multi-trait polygenic profile for dementia is associated with dementia- and disability-free survival in middle-aged and older adults. Background: Clinical trials of brain health and aging increasingly use holistic, patient-centered outcomes that capture overall health status....
Y. Tawaldemedhen, S. Clocchiatti-Tuozzo, C. Rivier et al.· medRxiv· 0 citations
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