Open access
Sep 2026
Lifelong Genetic Inhibition of PCSK9 and Hepatic Safety
This genetic association study investigates whether the full spectrum of rare PCSK9 loss-of-function variants is associated with incident liver-related outcomes, given the development of therapies targeting proprotein convertase subtilisin/kexin type 9 (PCSK9).
A. Di Costanzo, Ilaria Pirona, L. D'Erasmo et al.
· JAMA Network Open · 1 citation