Author

A. H. Nassar

2 papers indexed here

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#small language model Sep 2026

EGFR Mutation Subtype and Risk of Brain Metastases From Non-Small Cell Lung Cancer in the Osimertinib Era: EGFR Subtype and Brain Metastases in NSCLC.

Differences in brain metastasis development between EGFR L858R and Ex19Del mutations appeared to be mitigated among patients undergoing osimertinib compared with early-generation TKIs, representing an important systems bioengineering approach.

Ameya Patel, Victor Lee, A. H. Nassar et al. · American Journal of Clinical... · 0 citations

#gene editing Open access Sep 2026

Reverse genetics in humanized mice reveals CARD8-mediated pyroptosis causing pancytopenia in human DPP9 deficiency

Loss-of-function mutation in the human gene dipeptidyl peptidase 9 (DPP9) causes Hatipoglu syndrome leading to severe inflammasomopathy. A key feature of the disease is pancytopenia, and patients require bone marrow transplantation, but the mechanism of cell loss is unclear, since Dpp9-mutant mice have normal hematopoi...

Tian-Li Xiao, J. R. Brewer, Maximillian J. Carlino et al. · Journal of Clinical Investig... · 0 citations