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Author

A. Lärkeryd

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2 papers indexed here

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Open access Sep 2026

Spatially-resolved multimodal profiling identifies functionally-heterogeneous cancer-associated fibroblasts associated with poor radiotherapy outcomes in muscle-invasive bladder cancer

Background Cancer-associated fibroblasts (CAFs) contribute to systemic therapy resistance in muscle-invasive bladder cancer (MIBC), but their functional heterogeneity and relevance to curative bladder-preserving radiotherapy, are poorly understood. Methods Transcriptomic analysis was performed on 279 tumours from BC200...

Amy Burley, Katie O'Fee, Morgane Dromby et al. · 0 citations
#protein folding Open access Sep 2026

Collagen targeting IL-12 combined with doxorubicin enhances the anti-tumor effect against osteosarcoma.

It is demonstrated that CBD-IL-12 exhibited 4-fold enhanced tumor accumulation compared to unmodified IL-12 and increased cytotoxic T cell infiltration by 2.2-fold within the immune-cold microenvironment in a mouse model of OS.

Takumi Matsuo, Laurine Noblecourt, Pooja Kaur et al. · 0 citations

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