These findings uncover protein signatures that reflect underlying AD biology and provide a foundation for stage-specific biomarkers and therapeutic targeting, with important implications for patient stratification and personalized intervention strategies.
Saima Rathore, E. Dammer, Anantharaman Shantaraman et al.· Molecular Neurodegeneration· 0 citations
A Temporally-Aligned, Missingness-Aware, Interpretable (TAMI) multimodal fusion framework that aligns speech, language, facial, and physiological features within question-answer segments on a shared timeline, encodes modality-level missingness over time, and conditions fusion on question context is proposed.
M. Bibars, Bolaji Omofojoye, A. Levey et al.· 0 citations
Using human induced pluripotent stem cells (hiPSCs)‐derived neurons, human induced pluripotent stem cells were assayed how reducing gene expression of MSN and CD44 affected amyloid beta secretion, tau phosphorylation, and transcriptional state.
Eiden H. Brewer, Charles A. Williams, Gregory A. Cary et al.· Alzheimer's & Dementia· 0 citations
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