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Open access Sep 2026

CSF proteomics and machine learning reveal distinct stages across the Alzheimer’s disease continuum

These findings uncover protein signatures that reflect underlying AD biology and provide a foundation for stage-specific biomarkers and therapeutic targeting, with important implications for patient stratification and personalized intervention strategies.

Saima Rathore, E. Dammer, Anantharaman Shantaraman et al. · 0 citations
#artificial intelligence Preprint Aug 2026

TAMI: Temporally Aligned, Missingness-Aware, and Interpretable Multimodal Fusion for Mental Health Assessment in Older Adults with Mild Cognitive Impairment

A Temporally-Aligned, Missingness-Aware, Interpretable (TAMI) multimodal fusion framework that aligns speech, language, facial, and physiological features within question-answer segments on a shared timeline, encodes modality-level missingness over time, and conditions fusion on question context is proposed.

M. Bibars, Bolaji Omofojoye, A. Levey et al. · 0 citations
Open access Aug 2026

Inhibition of Moesin and CD44 in stem cell‐derived neurons affects the pathological genetic signature associated with Alzheimer's disease

Using human induced pluripotent stem cells (hiPSCs)‐derived neurons, human induced pluripotent stem cells were assayed how reducing gene expression of MSN and CD44 affected amyloid beta secretion, tau phosphorylation, and transcriptional state.

Eiden H. Brewer, Charles A. Williams, Gregory A. Cary et al. · 0 citations

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