Author

A. Mathew

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Review Aug 2026

Molecular cartography of breast cancer: decoding genomes, heterogeneity and the tumor microenvironment for personalized targeted therapeutics

A thorough examination of the tumor microenvironment was conducted, uncovering the complex involvement of immune cells in both protecting against and promoting tumor growth and tactics employed by tumors to evade the immune system.

A. Mathew, K. Ramalingam, Diya Gibu et al. · Molecular Biology Reports · 0 citations

Review Aug 2026

Breaking the relapse barrier: innovative approaches to improve CAR T-cell efficacy by targeting leukemic stem cells (LSCs) and measurable residual disease (MRD) in acute myeloid leukemia.

This review critically reviews the molecular signatures and protective mechanisms of relapse-initiating cells and introduces innovative CAR T cell engineering strategies that are aimed at disrupting the bone marrow niche, eliminating malignant stemness, overcoming exhaustion of engineered T cells and redefining the the...

A. Mathew, Ronak Raheja, Pranav Thomas Alex · International Immunopharmaco... · 0 citations