Author

A. Odermatt

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Open access Sep 2026

Hexose-6-phosphate dehydrogenase deficiency disrupts hepatic fatty acid homeostasis and induces triglyceride accumulation

The results indicate that H6PD plays an as-of-yet undescribed role in hepatic lipid metabolism, implying a link between the availability of NADPH within the endoplasmic reticulum and fatty acid homeostasis.

Gabriele Sakalauskaite, S. Ebert, J. Allard et al. · bioRxiv · 0 citations

Open access Aug 2026

Long-read target enrichment sequencing for rAAV integration site analysis in engineered clones with targeted viral insertion

Together, the engineered clonal controls and optimized LR-TES provide reference material and a technical framework supporting rAAV ISA in safety evaluation, particularly when high structural resolution and specificity are needed to interpret predominant integration events.

Erica Coratella, Myriam Lemmens, Mevion Oertli et al. · Molecular Therapy: Nucleic A... · 0 citations