Open access
Aug 2026
Genome-Wide in silico analysis reveals activation of a silent resistome driving imipenem resistance in Pseudomonas aeruginosa
This work proposes the “Silent Resistome Activation Model,” where resistance genes become functional only with support from identified accessory genes and coordinated interactions at both the genomic and network levels.
Sarfraz Anwar, A. R. Aromal, Ananya Anurag Anand et al.
· bioRxiv · 0 citations