BACKGROUND
Bipolar disorder (BD) studies consistently implicate the ventral prefrontal cortex (VPFC) in association with suicidal behaviors. A suicidal behavior polygenic risk score (PRS) can now be computed to test whether elevated genetic risk for suicidal behavior is associated with variation in VPFC gray matter and...
Noa Katz Shroitman, D. Levey, Brian P. Pittman et al.· Bipolar Disorders· 0 citations
Abstract Background Early life adversity (ELA) has been highlighted as strong distal factor for emergence of suicide behaviors (SB), however not all persons that experience ELA will engage in SB. Dispositional factors, such as stress system responsivity, emotion dysregulation, and brain structure and connectivity are h...
L. Colic, A. Sankar, A. Zerekidze et al.· International Journal of Neu...· 0 citations
Abstract Background Mood disorders are major contributors to the global burden of disease. There is a critical need for reliable markers that can identify individuals at elevated risk for developing mood disorders and predict poor prognosis among those already affected, in order to guide personalized interventions. Aim...
A. Sankar, B. Ozenne, V. Dam et al.· International Journal of Neu...· 0 citations
Abstract Background Cognitive impairments are common in individuals with depression, but their role in the etiology of the disorder remains unclear. Aims & Objectives In this 10-year longitudinal study, we tested whether cognitive function is associated with a risk for developing future first-episode depression in indi...
A. Sankar, B. Ozenne, V. Dam et al.· International Journal of Neu...· 0 citations
Older adults with bipolar disorder (BD) are at high risk for severe mood symptoms, cognitive difficulties, and early mortality; however, underlying brain alterations have received little study. Gray matter decreases in ventral prefrontal cortex (VPFC) seen in younger persons with BD, and additionally in dorsal PFC (DPF...
Rebecca B. Marks, A. Sankar, L. Colic et al.· Bipolar Disorders· 0 citations
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