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Sponsored Design Multi-Agent AI Systems Using MCP and A2A: Engineer your own Pyt Design Multi-Agent AI Systems Using MCP and A2A: Engineer your own Pyt

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A. Schinkel

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#protein folding Nov 2026

ABCB1, ABCG2, and CES1 are Key Determinants of the Pharmacokinetics of KRASG12C Inhibitor Divarasib

Divarasib is a selective KRASG12C inhibitor currently in phase 3 trials for treatment of NSCLC. Drug transporters and metabolic enzymes can markedly influence oral drug disposition. We therefore examined whether the efflux transporters ABCB1 and ABCG2, the influx transporter OATP1, and the enzymes CYP3A and CES1 affe...

J. Rijmers, Viët Bui, Daniëlle C. Band et al. · 0 citations

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