Improved pentose alcoholic fermentation in Ogataea polymorpha was achieved by positive selection and identification of the genetic determinants IRA1 and API1. Heterologous expression of lactate dehydrogenase genes enabled efficient L-lactic acid production, demonstrating distinct strategies for redirecting yeast metabo...
Roksolana Vasylyshyn, Aksyniia Tsaruk, Justyna Ruchała et al.· Achievements and Prospects o...· 0 citations
Candida famata is a flavinogenic non-conventional yeast with a high capacity for riboflavin (vitamin B₂) production and represents a promising microbial cell factory. Glycerol, particularly crude glycerol generated as a by-product of biodiesel production, is an attractive low-cost carbon source for microbial fermentati...
Alicja Najdecka, A. Sibirny· Achievements and Prospects o...· 0 citations
The non-conventional yeasts Ogataea polymorpha and Candida famata studied as hosts for the production of ethanol, L-lactic acid, and riboflavin from xylose, glycerol, and lignocellulosic hydrolysates provide a basis for further development of yeast-based production processes using lignocellulosic sugars and glycerol as...
A. Sibirny, Justyna Ruchała, Dominik Wojdyła et al.· Achievements and Prospects o...· 0 citations
A new factor of negative regulation of riboflavin biosynthesis in yeast C. famata was identified and encoded by the gene SEF2, which is focused on extension of the substrate range to produce the vitamin B2 such as whey and lignocellulose.
Dariya Fedorovych, K. Dmytruk, A. Sibirny· Achievements and Prospects o...· 0 citations
Overexpression of ADH6, HAA1, and GRE2 genes were performed and strains were characterized by increased in riboflavin production, characterized by increased in riboflavin production.
L. Dzanaeva, K. Dmytruk, A. Sibirny· Achievements and Prospects o...· 0 citations
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