Oct 2026
Personalized neoantigen-targeting cancer vaccines in ovarian cancer: a phase 1 trial.
Maclean C. Sellars, Jessica A. Frank, Bohoon Shim et al.
· Nature Medicine · 0 citations
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Jul 2026
Moving beyond the neutral-Darwinian dichotomy to inform precision oncology.
It is argued that tumour evolution is not a binary state, but a dynamic continuum shaped by genetic and non-genetic heterogeneity, spatial constraints, microenvironmental pressures and therapeutic bottlenecks, which will align these models with therapeutic decision-making in precision oncology.
A. Sud, R. Houlston
· npj Precision Oncology · 0 citations
Jul 2026
Tertiary lymphoid structures harbour stem-like tumour-specific T cells
Tertiary lymphoid structures are reservoirs of tumour-specific T cells with stem-like progenitor features that could be leveraged by T cell immunotherapies, and are found to be reservoirs of tumour-specific T cells with stem-like progenitor features that could be leveraged by T cell immune pressure.
Alexander B. Afeyan, Adi Nagler, Chloe R. Tu et al.
· Nature · 2 citations