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Review Open access Oct 2026

“Effects of different sedative agents in mechanically ventilated patients with sepsis: a GRADE-assessed systematic review and network meta-analysis”

The optimal sedative agent for mechanically ventilated adults with sepsis or septic shock remains uncertain. We evaluated the comparative effectiveness and safety of commonly used sedatives using network meta-analysis and GRADE. PubMed, Embase, Scopus, Cochrane Library, and ClinicalTrials.gov were searched...

Ume Aiman, Umer Bin Shahzad, Muhammad Aqib Farooq Khan et al. · 0 citations
Open access Jan 2026

Diabetes Mellitus Duration and Major Adverse Cardiovascular Events Following Percutaneous Coronary Intervention: A Prospective Cohort Study

Objective This study is aimed at evaluating the impact of Type 2 diabetes mellitus (T2DM) duration on major adverse cardiovascular events (MACEs) after percutaneous coronary intervention (PCI). Methods A single‐center prospective cohort study was conducted in which 465 T2DM patients undergoing PCI and completing the 1‐...

A. Tariq, Z. Bhatti, A. Khan et al. · 0 citations
Open access Aug 2026

An Empirical Study on the Prevalence and Multidrug Resistance Profiles of Salmonella and Campylobacter Species: A One Health Context

Salmonella and Campylobacter are foodborne pathogens that pose public health risks, particularly in commercial poultry production, where antimicrobial resistance may compromise the treatment of infected birds and undermine food safety. The present cross-sectional study aimed to determine the prevalence, antimicrobial r...

Muhammad Talha Aziz, Sadaf Sultana, Rabiya Sultana et al. · 0 citations
#gene editing Open access Sep 2026

Fluoxetine Hydrochloride Treatment Influences Site-Specific ADAR Editing and Transcriptome Regulation in Arid1b +/- Mice

Autism Spectrum Disorder (ASD) is a neurodevelopmental disorder characterized by repetitive behavior and impaired social interactions. Recent reports from human postmortem brain samples of ASD show transcriptome-wide dysregulations, including changes in differential gene expression and alternative splicing. An importan...

A. Tariq, H. Piontkivska · 0 citations

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