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Author

A. Vuorinen

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Preprint Sep 2026

PK/PD-integrated Bayesian platform design for phase II dose regimen optimization

A Bayesian phase II adaptive platform design for regimen optimization that integrates pharmacokinetic/pharmacodynamic (PK/PD) modelling into toxicity, efficacy, regimen selection and adaptation decisions is developed.

A. Vuorinen, A. Guillon, E. Comets et al. · 0 citations

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