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Author

Abdellatif El Khayari

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Aug 2026

Integrated single-cell profiling of RNA and DNA interactomes reveals targetable chromatin architectures in cancer

SCIENCE-seq is presented, a multimodal single-cell interactomics platform enabling simultaneous detection of RNA–RNA interactions and chromatin DNA–DNA contacts within individual cells and identifies a glioma-specific trans-chromosomal HOX hub driven by five interacting lncRNAs.

Evgeny Deforzh, Yanhong Zhang, H. Mnatsakanyan et al. · 0 citations

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