Author

Abhishek Kumar

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Open access Sep 2026

L-Serine and Palmitoyl CoA control Mycobacterial infection by tweaking protective immune response: A potential host directed therapy for tuberculosis

It is concluded that L-Serine and palmitic acid acts as a promising host-directed therapeutic adjunct, which enhances antimicrobial immunity and potentiating antibiotic efficacy, providing a potential strategy for improving tuberculosis treatment outcomes.

Niharika Sharma, Rahul Sharma, Abhishek Kumar et al. · bioRxiv · 0 citations

Open access Aug 2026

L-Serine potentiates the efficacy of Isoniazid, and Rifampicin as host-directed adjunctive treatment for Mycobacterium tuberculosis

L-Serine is an important metabolic and immunomodulatory biomolecule with promising role in managing infections, and autoimmune diseases. L-Serine provides the energy requirements and triggers the toll-like receptor signalling collaterally. However, the role of L-Serine in host antimicrobial response against Mycobacteri...

Niharika Sharma, Rahul Sharma, Abhishek Kumar et al. · bioRxiv · 0 citations

Open access Jul 2026

Pyrogallol inhibits T cell lymphoma growth by mediating G2/M phase cell cycle arrest, apoptosis, glycolysis and immune evasion: an implication of AKT pathway

Overall, this investigation demonstrates that pyrogallol exerts tumor growth inhibitory effect in T lymphoma cells by modulating the cell cycle, apoptosis, glucose metabolism, and immune evasion in an AKT-dependent manner.

Abhishek Kumar, Mukesh Kumar, Siddharth Rai et al. · Cytotechnology (Dordrecht) · 0 citations