The histone methyltransferase complex subunit RBBP5 serves as a central epigenetic regulator of proteostasis dynamics.
Proteostasis is essential for cellular health, with its disruption contributing to aging, neurodegeneration, and metabolic disorders. While the upstream proteotoxic stress-sensing and protein-folding mechanisms in the ER and cytosol are well studied, the transcriptional regulation of proteostasis remains incompletely u...
Syeda Kubra, Michelle Sun, William Dion et al.
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