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Sponsored Artificial Intelligence: A Modern Approach, Global Edition Artificial Intelligence: A Modern Approach, Global Edition

Author

Aksa Simon

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Review Sep 2026

The Metabolic-Epigenetic Axis in Cardiovascular Disease: Acylation Modifications as Metabolic Sensors Linking Cardiac Metabolism to the Epigenome

The ‘proposed cardiac epigenetic scar’ – the continued disruption of chromatin-modifying enzymes that prevents metabolic recovery in heart failure patients despite mechanical unloading, a concept from human LVAD studies is introduced.

Aksa Simon, Sunbee Prakash, J. Samuel · 0 citations

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