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Alana Coêlho Maciel

7 papers indexed here

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Open access Jul 2026

CHRONIC OBSTRUCTIVE PULMONARY DISEASE MORTALITY IN BRAZIL: TEMPORAL TRENDS, EPIDEMIOLOGICAL PROFILE, AND REGIONAL DIFFERENCES, 2010–2024

Objective: To analyze chronic obstructive pulmonary disease (COPD) mortality in Brazil from 2010 to 2024. Methods: An ecological time-series study used data from the Mortality Information System. COPD deaths (ICD-10: J44) were grouped into three five-year periods and analyzed by epidemiological profile, diagnostic category, and macroregion. Results: There were 573,482 deaths, an increase of 18.86%. J44.9 (unspecified COPD) accounted for approximately 85% of records. Men and people aged 60 years or older predominated, with increasing proportions of women and Black and Brown individuals. The Southeast had the largest number, whereas the Northeast and North showed the greatest proportional increases. Conclusion: Mortality remained high, with ageing of deaths, regional differences, and limited diagnostic specificity. Strengthening tobacco control, early diagnosis, exacerbation management, and death-cause certification is recommended.

Alana Coêlho Maciel, Thiago Emmanuel Araujo dos Santos, Renato Sarmento dos Reis Moreno et al. · 0 citations
Open access Jul 2026

EVOLUTION OF MORTALITY FROM SYSTEMIC ARTERIAL HYPERTENSION IN BRAZIL: TEMPORAL TRENDS, CHANGES IN DIAGNOSTIC PROFILE, AND SOCIODEMOGRAPHIC AND REGIONAL INEQUALITIES, 2010–2024

Objective: To analyze the evolution of mortality from systemic arterial hypertension in Brazil according to temporal trends, diagnostic profile, sociodemographic characteristics, and regional distribution from 2010 to 2024. Methods: This was an ecological time-series study using data from the Mortality Information System (SIM). Deaths whose underlying cause was classified in categories I10 to I15 of the International Statistical Classification of Diseases and Related Health Problems, Tenth Revision (ICD-10), corresponding to hypertensive diseases, were included. Records with unknown sex were proportionally redistributed. Data were grouped into three five-year periods and analyzed by diagnostic category, sex, age group, race/skin color, education, marital status, place of death, and macro-region, using frequencies and percentage variation. Results: A total of 816,407 deaths from hypertensive diseases were recorded, with a 43.83% increase between the first and last five-year periods. Essential hypertension (I10) remained the leading cause, increasing from 49.87% to 56.41%. Hypertensive heart disease (I11) decreased proportionally from 37.75% to 31.83%. Deaths predominated among women, people aged 60 years or older, individuals with low education, and widowed persons. Increases were observed among Black and Brown populations, along with fewer missing records, growth in home deaths, and increases in all macro-regions, especially the South. Conclusion: Mortality from hypertensive diseases increased markedly, reflecting population aging, diagnostic changes, and sociodemographic and regional inequalities.

Alana Coêlho Maciel, Renato Sarmento dos Reis Moreno, Ana Patrícia Barros Câmara et al. · 0 citations
Open access Jul 2026

MORTALITY FROM NEURODEGENERATIVE DISEASES IN BRAZIL: TEMPORAL TRENDS, CHANGES IN DIAGNOSTIC PROFILE, AND REGIONAL INEQUALITIES, 2010–2024

Objective: To analyze temporal trends in mortality from neurodegenerative diseases in Brazil, according to diagnostic categories of the International Statistical Classification of Diseases and Related Health Problems, Tenth Revision (ICD-10), sociodemographic characteristics, place of death, and regional distribution from 2010 to 2024. Methods: This was a nationwide ecological time-series study using data from the Mortality Information System (SIM/DATASUS). Deaths whose underlying cause was classified between G10 and G37 of ICD-10 were included. Records with unknown sex were proportionally redistributed. Data were grouped into three five-year periods and analyzed by diagnostic category, sex, age group, race/skin color, education, marital status, place of death, and macro-region, using absolute and relative frequencies and percentage variation. Results: A total of 435,791 deaths from neurodegenerative diseases were recorded, with a 113.00% increase between 2010–2014 and 2020–2024. Alzheimer’s disease (G30) remained the leading cause, accounting for approximately 70% of deaths and increasing by 112.72%. Other degenerative diseases of the nervous system (G31) showed the greatest proportional increase (272.81%), while Parkinson’s disease (G20) remained the second most frequent category. Female predominance, increasing concentration among individuals aged 60 years or older, growth among Black and Brown populations, fewer missing records, hospital predominance, and rising home deaths were observed. Conclusion: Mortality increased markedly, reflecting population aging, diagnostic changes, and regional inequalities.

Alana Coêlho Maciel, Renato Sarmento dos Reis Moreno, Ana Patricia Barros Camara et al. · 0 citations
Open access Aug 2026

THE SILENT RISE OF PANCREATIC CANCER IN BRAZIL: MAGNITUDE AND REGIONAL CONTRASTS IN MORTALITY, 2010–2024

Changing magnitude and sociodemographic and territorial inequalities reveal changing magnitude and sociodemographic and territorial inequalities, supporting cause-specific prevention, timely diagnosis, comprehensive care, and improved mortality information.

Getúlio Antônio de Freitas Filho, Alana Coêlho Maciel, Karla Danielly Xaveiro da Silva et al. · 0 citations
Open access Jul 2026

CEREBROVASCULAR DISEASE MORTALITY IN BRAZIL: TEMPORAL TRENDS, CHANGES IN THE DIAGNOSTIC PROFILE, AND SOCIODEMOGRAPHIC INEQUALITIES, 2010–2024

Mortality remains high and unequal, requiring cardiovascular prevention, improved stroke care pathways, rehabilitation, and reduction of regional inequities from 2010 to 2024.

Alana Coêlho Maciel, Renato Sarmento dos Reis Moreno, Ana Patrícia Barros Câmara et al. · 0 citations
Open access Jul 2026

CHRONIC KIDNEY DISEASE MORTALITY IN BRAZIL: TEMPORAL TRENDS, EPIDEMIOLOGICAL PROFILE, AND REGIONAL DIFFERENCES, 2010–2024

Chronic kidney disease mortality increased in Brazil, with ageing of deaths, persistent male excess mortality, an increasing share among Black and Brown individuals, and regional differences from 2010 to 2024.

Alana Coêlho Maciel, T. Santos, Renato Sarmento dos Reis Moreno et al. · 0 citations
Open access Jul 2026

CANCER MORTALITY IN BRAZIL: TEMPORAL TRENDS, CHANGES IN DIAGNOSTIC PROFILE, AND REGIONAL DIFFERENCES, 2010–2024

Neoplasm mortality increased markedly in Brazil, reflecting population aging, epidemiological transition, regional inequalities, and the need to strengthen prevention, screening, early diagnosis, oncology care, surveillance, equity, and health information.

Alana Coêlho Maciel, Renato Sarmento dos Reis Moreno, Ana Patrícia Barros Câmara et al. · 0 citations