Jul 2026· Revista de Estudos Interdisciplinares· 0 citations
TL;DR
Mortality remains high and unequal, requiring cardiovascular prevention, improved stroke care pathways, rehabilitation, and reduction of regional inequities from 2010 to 2024.
Abstract
Objective: To analyze temporal trends in cerebrovascular disease mortality in Brazil, considering changes in the diagnostic profile, sociodemographic characteristics, place of death, and regional distribution from 2010 to 2024. Methods: This was a nationwide ecological time-series study using data from the Mortality Information System (SIM/DATASUS). Deaths classified under codes I60 to I69 of the International Statistical Classification of Diseases and Related Health Problems, Tenth Revision (ICD-10), were included. Records with unknown sex were proportionally redistributed. Data were grouped into three five-year periods and analyzed by diagnostic category, sex, age group, race/skin color, education, marital status, place of death, and macro-region, using absolute and relative frequencies and sex ratio. Results: A total of 1,526,062 deaths from cerebrovascular diseases were recorded, with a 4.1% increase between the first and last five-year periods. Unspecified stroke (I64) remained the leading cause, although its share declined from 43.0% to 33.5%. Conversely, cerebral infarction (I63) increased from 4.2% to 11.4%, and sequelae of cerebrovascular diseases (I69) from 16.5% to 18.6%, suggesting improved diagnostic specification. Mortality was concentrated among individuals aged 60 years or older, with a slight male predominance, proportional growth among Black and Brown populations, relative increase in the North Region, and hospital predominance. Conclusion: Mortality remains high and unequal, requiring cardiovascular prevention, improved stroke care pathways, rehabilitation, and reduction of regional inequities.
Chronic kidney disease mortality increased in Brazil, with ageing of deaths, persistent male excess mortality, an increasing share among Black and Brown individuals, and regional differences from 2010 to 2024.
Alana Coêlho Maciel, T. Santos, Renato Sarmento dos Reis Moreno et al.· Revista de Estudos Interdisc...· 0 citations
Objective: To analyze the evolution of mortality from systemic arterial hypertension in Brazil according to temporal trends, diagnostic profile, sociodemographic characteristics, and regional distribution from 2010 to 2024. Methods: This was an ecological time-series study using data from the Mortality Information System (SIM). Deaths whose underlying cause was classified in categories I10 to I15 of the International Statistical Classification of Diseases and Related Health Problems, Tenth Revision (ICD-10), corresponding to hypertensive diseases, were included. Records with unknown sex were proportionally redistributed. Data were grouped into three five-year periods and analyzed by diagnostic category, sex, age group, race/skin color, education, marital status, place of death, and macro-region, using frequencies and percentage variation. Results: A total of 816,407 deaths from hypertensive diseases were recorded, with a 43.83% increase between the first and last five-year periods. Essential hypertension (I10) remained the leading cause, increasing from 49.87% to 56.41%. Hypertensive heart disease (I11) decreased proportionally from 37.75% to 31.83%. Deaths predominated among women, people aged 60 years or older, individuals with low education, and widowed persons. Increases were observed among Black and Brown populations, along with fewer missing records, growth in home deaths, and increases in all macro-regions, especially the South. Conclusion: Mortality from hypertensive diseases increased markedly, reflecting population aging, diagnostic changes, and sociodemographic and regional inequalities.
Alana Coêlho Maciel, Renato Sarmento dos Reis Moreno, Ana Patrícia Barros Câmara et al.· Revista de Estudos Interdisc...· 0 citations
Neoplasm mortality increased markedly in Brazil, reflecting population aging, epidemiological transition, regional inequalities, and the need to strengthen prevention, screening, early diagnosis, oncology care, surveillance, equity, and health information.
Alana Coêlho Maciel, Renato Sarmento dos Reis Moreno, Ana Patrícia Barros Câmara et al.· Revista de Estudos Interdisc...· 0 citations
Objective: To analyze temporal trends in mortality from neurodegenerative diseases in Brazil, according to diagnostic categories of the International Statistical Classification of Diseases and Related Health Problems, Tenth Revision (ICD-10), sociodemographic characteristics, place of death, and regional distribution from 2010 to 2024. Methods: This was a nationwide ecological time-series study using data from the Mortality Information System (SIM/DATASUS). Deaths whose underlying cause was classified between G10 and G37 of ICD-10 were included. Records with unknown sex were proportionally redistributed. Data were grouped into three five-year periods and analyzed by diagnostic category, sex, age group, race/skin color, education, marital status, place of death, and macro-region, using absolute and relative frequencies and percentage variation. Results: A total of 435,791 deaths from neurodegenerative diseases were recorded, with a 113.00% increase between 2010–2014 and 2020–2024. Alzheimer’s disease (G30) remained the leading cause, accounting for approximately 70% of deaths and increasing by 112.72%. Other degenerative diseases of the nervous system (G31) showed the greatest proportional increase (272.81%), while Parkinson’s disease (G20) remained the second most frequent category. Female predominance, increasing concentration among individuals aged 60 years or older, growth among Black and Brown populations, fewer missing records, hospital predominance, and rising home deaths were observed. Conclusion: Mortality increased markedly, reflecting population aging, diagnostic changes, and regional inequalities.
Alana Coêlho Maciel, Renato Sarmento dos Reis Moreno, Ana Patricia Barros Camara et al.· Revista de Estudos Interdisc...· 0 citations
Objective: To analyze chronic obstructive pulmonary disease (COPD) mortality in Brazil from 2010 to 2024. Methods: An ecological time-series study used data from the Mortality Information System. COPD deaths (ICD-10: J44) were grouped into three five-year periods and analyzed by epidemiological profile, diagnostic category, and macroregion. Results: There were 573,482 deaths, an increase of 18.86%. J44.9 (unspecified COPD) accounted for approximately 85% of records. Men and people aged 60 years or older predominated, with increasing proportions of women and Black and Brown individuals. The Southeast had the largest number, whereas the Northeast and North showed the greatest proportional increases. Conclusion: Mortality remained high, with ageing of deaths, regional differences, and limited diagnostic specificity. Strengthening tobacco control, early diagnosis, exacerbation management, and death-cause certification is recommended.
Alana Coêlho Maciel, Thiago Emmanuel Araujo dos Santos, Renato Sarmento dos Reis Moreno et al.· Revista de Estudos Interdisc...· 0 citations
Abstract Objective: To describe the temporal and spatial distribution of cardiovascular disease mortality in Brazil from 2003 to 2023. Methods: A time series and spatial analysis study was conducted using secondary data from the Mortality Information System run by the Brazilian Unified Health System Department of Information Technology, including all deaths from circulatory system diseases. Sociodemographic characteristics were analyzed and standardized mortality rates per 100,000 inhabitants were calculated. The temporal trend was assessed using joinpoint regression, with estimated annual percentage change. The spatial analysis considered average municipal rates, both unadjusted and also smoothed by the local empirical Bayesian method, in addition to global and local spatial autocorrelation. Results: 7,088,623 cardiovascular disease deaths were recorded in Brazil between 2003 and 2023, with predominance in males and higher mortality rates among the elderly and people with low levels of education. The highest rates were observed in the Southeast (190.14/100,000) and Southern (187.59/100,000) regions, while the Northern (APC 2003-2008 4.38; APC 2008-2023 2.33) and Northeast (APC 2003-2007 8.15; APC 2007-2023 1.11) regions showed an increasing trend over the period (p-value<0.001). Global Moran’s I (0.02; p-value<0.05) indicated weak but statistically significant positive spatial autocorrelation. Local analysis revealed clusters of high mortality concentrated mainly in municipalities of Mato Grosso and Goiás states, while areas of low mortality predominated in the Northern region and on the Northeast coast. Conclusion: Cardiovascular disease mortality in Brazil showed heterogeneous distribution in time and space.
Francisca Vaneska Lima Nascimento, Ítalo Rigoberto Cavalcante Andrade, Lara Lídia Ventura Damasceno et al.· Epidemiologia e Serviços de...· 0 citations