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Aleksandra Blachucik

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Review Open access Oct 2026

Pediatric inflammatory bowel disease: a review of current research

Inflammatory bowel disease (IBD), comprising Crohn’s disease (CD) and ulcerative colitis, is a growing global health challenge, with approximately 25% of cases diagnosed before the age of 20. These chronic immune- mediated disorders result from complex interactions between genetic predisposition, environmental triggers...

Alina Mykhalevych, Julia Grygorowicz, Monika Sas-Wyżykowska et al. · 0 citations
Review Open access Sep 2026

Probiotics in Atopic Dermatitis: Does Gut Microbiome Modulation Enhance Skin Condition?

Abstract Atopic dermatitis (AD) is a chronic condition driven by epidermal barrier disruption and multiphasic immune dysregulation involving type 2, Th1, Th17, and Th22 pathways. Beyond local cutaneous pathology, systemic interactions mediated by the bidirectional gut–skin axis play an integral role, in which intestina...

Kamila Łukańko, Aleksandra Blachucik, W. Marciniak et al. · 0 citations
Review Open access Sep 2026

DEXMEDETOMIDINE FOR SEDATION IN CHILDREN – A NARRATIVE REVIEW OF CLINICAL EVIDENCE, SAFETY CONSIDERATIONS, AND EMERGING THERAPEUTIC ROLES

Dexmedetomidine is a highly selective alfa2-adrenergic agonist increasingly used in pediatric anesthesia and intensive care because of its unique sedative profile and minimal respiratory depressive effects. This narrative summarizes current evidence regarding the pharmacology, pharmacokinetics, clinical efficacy, safet...

Gabriela Faria, Anna Wyżykowska, M. Maruszak et al. · 0 citations
Review Open access Sep 2026

GUT MICROBIOTA AND THE GUT–BRAIN AXIS IN ANXIETY DISORDERS: CURRENT EVIDENCE AND THERAPEUTIC PERSPECTIVES

Current evidence indicates that gut microorganisms moderate central nervous system functioning through neural, immunological, endocrine, and metabolic pathways, and available evidence indicates that gut microorganisms moderate central nervous system functioning through neural, immunological, endocrine, and metabolic pa...

Monika Sas-Wyżykowska, Anna Wyżykowska, M. Maruszak et al. · 0 citations
Review

Innovative Technologies in Social

A review of key diagnostic challenges and current approaches to pharmacological management of depression and anxiety in advanced cancer, with particular emphasis on palliative care populations, indicates that standard diagnostic criteria may have limited applicability in medically ill patients.

Anna Wyżykowska, M. Maruszak, Julia Grygorowicz et al. · 0 citations
Review Open access Jul 2026

The Role of the Gut-Brain Axis in the Pathogenesis and Treatment of Irritable Bowel Syndrome in Children and Adolescents: A Review of Current Research with Focus on Dietary and Psychoneurogastroenterological Interventions

The MGBA represents the primary therapeutic target in pediatric IBS, supporting multimodal approaches, but limitations in pediatric-specific evidence suggest the need for high-quality randomized controlled trials with standardized outcome measures and adequate long-term follow-up.

Julia Grygorowicz, M. Maruszak, Anna Wyżykowska et al. · 0 citations
Review Open access Jul 2026

Modern Directions in Early Biomarker Diagnostics of Parkinson's Disease

Multimodal biomarker panels integrating molecular, microvascular, and imaging data provide the most precise risk stratification, enabling timely, targeted neuroprotective interventions by rehabilitation specialists.

Aliaksandr Kryshtofik, Julia Grygorowicz, Gabriela Faria et al. · 0 citations

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