Inflammatory bowel disease (IBD), comprising Crohn’s disease (CD) and ulcerative colitis, is a growing global health challenge, with approximately 25% of cases diagnosed before the age of 20. These chronic immune- mediated disorders result from complex interactions between genetic predisposition, environmental triggers...
Alina Mykhalevych, Julia Grygorowicz, Monika Sas-Wyżykowska et al.· Pediatria Polska· 0 citations
Abstract Atopic dermatitis (AD) is a chronic condition driven by epidermal barrier disruption and multiphasic immune dysregulation involving type 2, Th1, Th17, and Th22 pathways. Beyond local cutaneous pathology, systemic interactions mediated by the bidirectional gut–skin axis play an integral role, in which intestina...
Kamila Łukańko, Aleksandra Blachucik, W. Marciniak et al.· Advances in microbiology· 0 citations
Dexmedetomidine is a highly selective alfa2-adrenergic agonist increasingly used in pediatric anesthesia and intensive care because of its unique sedative profile and minimal respiratory depressive effects. This narrative summarizes current evidence regarding the pharmacology, pharmacokinetics, clinical efficacy, safet...
Gabriela Faria, Anna Wyżykowska, M. Maruszak et al.· International Journal of Inn...· 0 citations
Current evidence indicates that gut microorganisms moderate central nervous system functioning through neural, immunological, endocrine, and metabolic pathways, and available evidence indicates that gut microorganisms moderate central nervous system functioning through neural, immunological, endocrine, and metabolic pa...
Monika Sas-Wyżykowska, Anna Wyżykowska, M. Maruszak et al.· International Journal of Inn...· 0 citations
A review of key diagnostic challenges and current approaches to pharmacological management of depression and anxiety in advanced cancer, with particular emphasis on palliative care populations, indicates that standard diagnostic criteria may have limited applicability in medically ill patients.
Anna Wyżykowska, M. Maruszak, Julia Grygorowicz et al.· 0 citations
The MGBA represents the primary therapeutic target in pediatric IBS, supporting multimodal approaches, but limitations in pediatric-specific evidence suggest the need for high-quality randomized controlled trials with standardized outcome measures and adequate long-term follow-up.
Julia Grygorowicz, M. Maruszak, Anna Wyżykowska et al.· Journal of Education, Health...· 0 citations
Multimodal biomarker panels integrating molecular, microvascular, and imaging data provide the most precise risk stratification, enabling timely, targeted neuroprotective interventions by rehabilitation specialists.
Aliaksandr Kryshtofik, Julia Grygorowicz, Gabriela Faria et al.· Quality in Sport· 0 citations
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