Amaresh Jana

Vibrio cholerae VgrG1-ACD Targets E. coli MreB and Regulates Cellular Morphology

This work identifies a previously unrecognized bacterial target of VgrG1-ACD: MreB, the bacterial actin homolog essential for cell shape, cell wall synthesis, and cytoskeletal organization and uncovers a dual-targeting strategy through which a single T6SS effector manipulates both mammalian actin and its bacterial homo...