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Anastasia S. Samok

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#protein folding Open access Aug 2026

Stable Constitutive BiP Expression Prolongs Late-Stage GLP-1–Fc Accumulation in CHO Cells

Stable constitutive expression of host-derived BiP was associated with prolonged late-stage GLP-1–Fc accumulation in the producer population examined, and these kinetics are compatible with a model in which the timing of ER chaperone supply influences the maintenance of productive output.

R. R. Shaifutdinov, Fedor A. Krukov, Anastasia S. Samok et al. · 0 citations