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Sponsored Artificial Intelligence: A Modern Approach, Global Edition Artificial Intelligence: A Modern Approach, Global Edition

Author

Andrea Gottinger

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Open access Sep 2026

Cryo-EM reveals the central steps of mitochondrial complex III assembly and the cooperative assembly of supercomplex CIII2CIV

A generalizable model for the maturation of the complex is proposed, alongside a model for supercomplex formation that supports the cooperative assembly model, and the central role of cryo-EM is showcased in the study of assembly mechanism of protein complexes.

Ahad Ali Kazmi, Andrea Gottinger, Marine S. Huhardeaux et al. · 0 citations
Open access Sep 2026

AI-enhanced adaptive virtual screening of large libraries for ligand discovery.

AdaptiveFlow enables drug discovery at unprecedented scale and supports the development of AI-driven methods, and identifies nanomolar inhibitors of two disease-relevant targets, ferroptosis suppressor protein 1 and poly(ADP-ribose) polymerase 1.

Domiziana Cecchini, AkshatKumar Nigam, Ming Tang et al. · 1 citation

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