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Author

Andrea Vandelli

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#protein folding Open access Oct 2026

A circRNA-derived IRES-like element enables programmable translational activation of the endogenous chaperone HSP90

SynFarsa is characterized, a synthetic circRNA-derived IRES-like element that promotes cap-independent translation in mouse and human cells and provides a circRNA-derived effector domain for targeted translational upregulation of an endogenous protein.

Guy Aoun, Andrea Vandelli, Riccardo Delli Ponti et al. · 0 citations
Open access Aug 2026

The human RNA-DNA interactome is cell type-specific and dynamic

The RNA-DNA interactome is established as a new genome regulatory layer that defines and maintains cellular identity and behavior and is shown to be highly dynamic yet reproducibly organized in cell-type specific networks.

A. Lambolez, P. Sahlén, Wenjing Kang et al. · 1 citation

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