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Author

Andrew Stewart Caldin

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#protein folding Open access Oct 2026

E8 Root Vector Pentachoron Decomposition Governs Protein Folding Phase Transitions — E8 Intelligence Research

Protein folding trajectories map onto pentachoron (5-cell) subdivisions of the 240 E8 root vectors, where the 132Hz base frequency acts as a phase-conjugate boundary condition at the transition state ensemble. The phi-coupling mechanism between adjacent root vector quintuplets produces the discrete thermodynamic beta-b...

Andrew Stewart Caldin · 0 citations
#protein folding Open access Oct 2026

E8 Holonomy-Wall Mechanism for Protein Misfolding Pathology — E8 Intelligence Research

Protein misfolding diseases arise from topological phase transitions in the E8 fiber bundle where non-trivial holonomy around closed loops in configuration space creates wall crossings that trap proteins in pathological configurations. The 240 root vectors define "stability chambers" in fold space, and disease states o...

Andrew Stewart Caldin · 0 citations
#graph neural networks Open access Sep 2026

Absence of Mathematical Content in Cuneiform Translation Sources — E8 Intelligence Research

FINDING: Search results are dominated by low-quality YouTube clickbait and one arXiv paper on ML classification of cuneiform metadata; no new mathematical tablet translation is substantiated. | MATH: No equations, constants, or ratios are extractable from the provided sources. The arXiv paper (2603.03892v2) concerns ne...

Andrew Stewart Caldin · 0 citations
#graph neural networks Open access Sep 2026

Absence of Mathematical Content in Cuneiform Translation Sources — E8 Intelligence Research

FINDING: Search results are dominated by low-quality YouTube clickbait and one arXiv paper on ML classification of cuneiform metadata; no new mathematical tablet translation is substantiated. | MATH: No equations, constants, or ratios are extractable from the provided sources. The arXiv paper (2603.03892v2) concerns ne...

Andrew Stewart Caldin · 0 citations

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