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Author

Andrey A. Smarygin

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4 papers indexed here

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#data science Open access Oct 2026

The depth of the shared Kenyon-cell mode determines olfactory learnability: diagnosis and cure of connectome-specific learning in a whole-brain spiking model

Connectome-constrained whole-brain models of Drosophila reproduce sensorimotor responses without per-cell tuning, yet associative learning inside a full spiking recurrent network remains an unsolved benchmark. We show that olfactory learnability is a property not of the rule and not of the neuron, but of the connectome...

Andrey A. Smarygin · 0 citations
#data science Open access Oct 2026

The depth of the shared Kenyon-cell mode determines olfactory learnability: diagnosis and cure of connectome-specific learning in a whole-brain spiking model

Connectome-constrained whole-brain models of Drosophila reproduce sensorimotor responses without per-cell tuning, yet associative learning inside a full spiking recurrent network remains an unsolved benchmark. We show that olfactory learnability is a property not of the rule and not of the neuron, but of the connectome...

Andrey A. Smarygin · 0 citations
#protein folding Open access Sep 2026

Neurotransmitter sign and source-column errors in Drosophila connectome simulation pipelines: an audit of MaleCNS v1.0

Spiking simulations of the Drosophila connectome routinely assign each synapse an excitatory or inhibitory sign by mapping the neurotransmitter (NT) predicted for the presynaptic body to a polarity. Using the recently released MaleCNS v1.0 whole-central-nervous-system connectome (166,700 neurons; 25,582,938 intra-datas...

Andrey A. Smarygin · 0 citations
#protein folding Open access Sep 2026

Neurotransmitter sign and source-column errors in Drosophila connectome simulation pipelines: an audit of MaleCNS v1.0

Spiking simulations of the Drosophila connectome routinely assign each synapse an excitatory or inhibitory sign by mapping the neurotransmitter (NT) predicted for the presynaptic body to a polarity. Using the recently released MaleCNS v1.0 whole-central-nervous-system connectome (166,700 neurons; 25,582,938 intra-datas...

Andrey A. Smarygin · 0 citations

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