A metabolite-guided signal fidelity hypothesis is proposed in which certain specialized metabolites act as molecular stabilizers in the response of organisms to stress and buffer transient ROS bursts, limit variability in calcium signaling, and strengthen hormone-regulated feedback loops.
M. Warda, Merve Bolat, S. Tekin et al.· Plants· 0 citations
It is demonstrated that rosmarinic acid exerts potent neuroprotective effects against INH-induced brain injury by simultaneously targeting oxidative stress, mitochondrial dysfunction, iron dyshomeostasis, neuroinflammation, ferroptosis, and apoptosis.
Merve Bolat, Tuba Karaarslan, S. Tekin et al.· Tissue & Cell· 0 citations
Findings indicate that Morin exerts a strong nephroprotective effect against Cd-induced renal toxicity through attenuation of oxidative stress and inflammation, possibly associated with its antioxidant and anti-inflammatory properties.
Burak Batuhan Laçin, Furkan Aykurt, S. Tekin et al.· Erciyes Üniversitesi Veterin...· 0 citations
It is suggested that p-coumaric acid exerts neuroprotective effects against PbAc-induced brain injury by attenuating oxidative stress, neuroinflammation, and apoptosis while supporting neuronal plasticity.
Tuba Karaarslan, Merve Bolat, İsmail Bolat et al.· Biological Trace Element Res...· 0 citations
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