p-Coumaric Acid Attenuates Lead Acetate-induced Neurotoxicity in Rats by Improving Behavioral Dysfunction and Suppressing Oxidative Stress, Neuroinflammation, Apoptosis, and Plasticity-related Molecular Alterations.
Aug 2026· Biological Trace Element Research· 0 citations· 7 references
Medicine
TL;DR
It is suggested that p-coumaric acid exerts neuroprotective effects against PbAc-induced brain injury by attenuating oxidative stress, neuroinflammation, and apoptosis while supporting neuronal plasticity.
EA attenuates scopolamine-induced memory deficits, accompanied by improvements in oxidative stress markers, neuroinflammatory gene expression, and cholinergic parameters, which suggest a potential neuroprotective role of EA.
Arezoo Rajabian, Amir Hossein Assaran, Farshad Mirzavi et al.· Research in Pharmaceutical S...· 0 citations
Overall, ZIN exhibited dose-dependent hepatoprotective and neuroprotective effects in TAA-induced hepatic encephalopathy, as evidenced by attenuation of oxidative stress, inflammation, ER stress, and apoptosis.
Furkan Aykurt, S. Yıldırım, Metin Kılıçlıoğlu et al.· Journal of Molecular Histolo...· 0 citations
BACKGROUND
Erucic acid (EA), a monounsaturated omega-9 fatty acid derived from Raphanus sativus L. seeds, has antioxidant and anti-inflammatory properties. This study investigated its neuroprotective effects against streptozotocin (STZ)-induced diabetes-associated cognitive dysfunction in rats.
METHODS
Male Wistar ra...
N. Sayyed, M. Afzal, Misbahudin Rafeeq et al.· Nutritional neuroscience· 0 citations
BLN exhibits considerable neuroprotective properties against CIS‐induced neurotoxicity in the hippocampus, suggesting its potential as a natural dietary phytonutrient supplement to ameliorate chemotherapy‐induced cognitive impairment.
R. U. Syed, R. Akasha, N. Elafandy et al.· Journal of biochemical and m...· 0 citations
It is demonstrated that ferulic acid attenuates the long-term behavioral and neurochemical consequences of ELS and support further investigation of its neuroprotective potential in stress-related neurobehavioral disorders.
Simran, Varinder Singh, N. Kanwar et al.· 3 Biotech· 1 citation
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