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S. Tekin

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Open access Sep 2026

Plant Stress Signaling in a Cross-Kingdom Context: Metabolic Control of Redox and ROS-Ca2+-Hormone Interactomes

Biological systems maintain functional integrity under environmental stress through tightly coordinated signaling networks, yet the mechanisms that preserve signal fidelity in the presence of stochastic oxidative and ionic fluctuations across taxa remain incompletely understood. Although redox regulation, coupling betw...

Mohamad Warda, Merve Bolat, S. Tekin et al. · 0 citations
Aug 2026

Rosmarinic Acid Attenuates Isoniazid-Induced Neurotoxicity by Restoring Mitochondrial Dynamics and Suppressing Oxidative Stress, Ferroptosis, Neuroinflammation, and Apoptosis.

Despite the continued global burden of tuberculosis and the essential role of isoniazid (INH) in first-line antituberculosis therapy, INH-induced neurotoxicity remains a major clinical challenge that compromises treatment adherence, and effective, well-characterized neuroprotective strategies are still lacking. This st...

Merve Bolat, Tuba Karaarslan, S. Tekin et al. · 0 citations
Open access Aug 2026

Morin Protects Against Cadmium-Induced Acute Renal Toxicity by Reducing Oxidative Stress and Inflammation

Findings indicate that Morin exerts a strong nephroprotective effect against Cd-induced renal toxicity through attenuation of oxidative stress and inflammation, possibly associated with its antioxidant and anti-inflammatory properties.

Burak Batuhan Laçin, Furkan Aykurt, S. Tekin et al. · 0 citations
Jul 2026

Neuroprotective effects of zingerone on the thioacetamide-induced hepatic encephalopathy in rats. Insights from oxidative stress, ER stress, BDNF signaling and apoptosis

Overall, ZIN exhibited dose-dependent hepatoprotective and neuroprotective effects in TAA-induced hepatic encephalopathy, as evidenced by attenuation of oxidative stress, inflammation, ER stress, and apoptosis.

Furkan Aykurt, S. Yıldırım, Metin Kılıçlıoğlu et al. · 0 citations
Aug 2026

Morin attenuates vancomycin-induced nephrotoxicity via Nrf-2/HO-1, SIRT1/PGC1α and AKT/FOXO1A pathways

Morin (MOR) treatment significantly ameliorated VCM-induced renal injury by reducing oxidative injury, restoring endogenous defense systems, attenuating inflammatory responses, suppressing apoptosis, and markedly improving histopathological lesions.

S. Tekin, Merve Bolat, Burak Batuhan Laçin et al. · 0 citations
Aug 2026

p-Coumaric Acid Attenuates Lead Acetate-induced Neurotoxicity in Rats by Improving Behavioral Dysfunction and Suppressing Oxidative Stress, Neuroinflammation, Apoptosis, and Plasticity-related Molecular Alterations.

It is suggested that p-coumaric acid exerts neuroprotective effects against PbAc-induced brain injury by attenuating oxidative stress, neuroinflammation, and apoptosis while supporting neuronal plasticity.

Tuba Karaarslan, Merve Bolat, İsmail Bolat et al. · 0 citations

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