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Author

Aylin del Moral-Morales

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2 papers indexed here

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Review Open access Aug 2026

Advances in the emerging field of epi-informatics in drug discovery: roads taken and future prospects.

An updated overview of bioinformatics, chemoinformatics, and machine learning methodologies used to identify, design, and optimize compounds that modulate epigenetic processes with therapeutic potential and examines the epigenetic drug discovery landscape by analyzing the most extensively investigated epigenetic target...

Aylin del Moral-Morales, Erik D. Díaz-Dionisio, Josė L. Medina-Franco · 0 citations
#protein folding Open access Aug 2026

Ser715 Phosphorylation Induces β-Hairpin Unfolding and Destabilization of FOXM1 Autoinhibition.

FOXM1 is a cell proliferation-driving transcription factor activated by phosphorylation-induced conformational changes. In its inactive state, an intramolecular β-hairpin within the transactivation domain (TAD) binds the N-terminal repressor domain (NRD), forming a composite β-sheet that locks the protein in an autoinh...

Sara AlRawashdeh, Raghd Obidat, Aylin del Moral-Morales et al. · 0 citations

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