Ayusha O. Dondulkar

Electrospun dual flavonoid-loaded polyacrylonitrile nanofibers for accelerated diabetic wound healing via NF-κB and TNF-α modulation.

Electrospun nanofibers of polyacrylonitrile loaded with apigenin and naringenin as an effective strategy to promote diabetic wound healing have been developed and revealed that the nanofibers accelerate wound healing and lead to wound closure of 96.23% on day 14 along with enhanced epithelialization, collagen synthesis, and inhibition of NF-κB and TNF-α expression.