coronavirus hemagglutinin-esterase receptor-binding site: a major shift in ligand specificity through modest changes in architecture
The crystal structure of the lectin domain of mouse hepatitis virus (MHV) strain S HE is presented, resolved both in its native state and in complex with a receptor analogue, illustrating the ease with which viruses can change receptor-binding specificity.
M. Langereis, Q. Zeng, B. Heesters et al.
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