Author

B. Navarro

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Open access Sep 2026

A newly established reverse genetic system for a circular RNA virus reveals new requirements for infection and its biocontrol potential

This work constructed the first infectious cDNA clone of an ambivirus, Fusarium graminearum ambivirus 1 (FgAV1), using a head-to-tail dimer placed downstream of a fungal promoter, demonstrating that FgAV1 infection triggers a fungal RNAi response, extending the antiviral role of host sRNAs to circular RNA viruses.

Yi Guo, M. Forgia, N. Serale et al. · Science Advances · 0 citations

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