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B. Sireesha

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Open access Sep 2026

ANALYTICAL QUALITY BY DESIGN-ASSISTED DEVELOPMENT AND VALIDATION OF A RAPID STABILITY-INDICATING GRADIENT ULTRA-PERFORMANCE LIQUID CHROMATOGRAPHY METHOD FOR SIMULTANEOUS ESTIMATION OF EMPAGLIFLOZIN, SACUBITRIL, AND VALSARTAN IN PHARMACEUTICAL DOSAGE FORMS

Objectives: Simultaneous estimation of empagliflozin, sacubitril, and valsartan in combined pharmaceutical formulations is analytically challenging due to their differing polarity, physicochemical properties, and chromatographic retention behavior. Conventional high-performance liquid chromatography methods often requi...

B. Sireesha, Saravanan Ravindran · 0 citations
Review

Emerging Role of Human Organoids in Drug Discovery and Development: Current Advances and Challenges

Overall, organoid technology represents a promising approach for precision medicine, personalized therapy, and next-generation drug development and continued development of standardized culture systems and multicellular organoid platforms may improve reproducibility and regulatory acceptance.

B. Sireesha, S. Meharaj, Saravanan Ravindran · 0 citations

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